Phosphoglucan, water dikinase

In enzymology, a phosphoglucan, water dikinase (EC 2.7.9.5) is an enzyme that catalyzes the chemical reaction

ATP + [phospho-alpha-glucan] + H2O AMP + O-phospho-[phospho-alpha-glucan] + phosphate
Phosphoglucan, water dikinase
Identifiers
EC number2.7.9.5
CAS number912567-76-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The 3 substrates of this enzyme are ATP, phospho-alpha-glucan, and H2O, whereas its 3 products are AMP, [[O-phospho-[phospho-alpha-glucan]]], and phosphate.

This enzyme belongs to the family of transferases, to be specific, those transferring phosphorus-containing groups (phosphotransferases) with paired acceptors (dikinases). The systematic name of this enzyme class is ATP:phospho-alpha-glucan, water phosphotransferase. Other names in common use include PWD, and OK1.

References

    • Kotting O, Pusch K, Tiessen A, Geigenberger P, Steup M, Ritte G (2005). "Identification of a novel enzyme required for starch metabolism in Arabidopsis leaves. The phosphoglucan, water dikinase". Plant Physiol. 137 (1): 242–52. doi:10.1104/pp.104.055954. PMC 548855. PMID 15618411.
    • Ritte G, Heydenreich M, Mahlow S, Haebel S, Kotting O, Steup M (2006). "Phosphorylation of C6- and C3-positions of glucosyl residues in starch is catalysed by distinct dikinases". FEBS Lett. 580 (20): 4872–6. doi:10.1016/j.febslet.2006.07.085. PMID 16914145.


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