Rahul Potluri

Potluri and the ACALM Study Unit showed for the first time in humans, a possible association between high cholesterol and breast cancer. This work was presented at the European Society of Cardiology, Frontiers in Cardiovascular Biology Conference in Barcelona, July 2014 and was widely reported in the global media.[2][4][5][6][7][8][9] Further research presented in 2016 showed the role of high cholesterol and possibly the role of statins improving the mortality and survival of patients with breast cancer, lung cancer, bowel cancer and prostate cancer and strengthening calls for a clinical trial of statins in cancer.[9][10][11]

Potluri presented research from the ACALM Study Unit at the European Society of Cardiology Conference in London, August 2015, which showed that heart attack patients admitted at the weekend died earlier compared to those admitted during the working week.[12][13] Subsequent research looking at patients discharged from UK hospitals at the weekend had significantly worsened mortality and survival compared to those discharged during the working week.[14][15] This was the first study of its kind from the UK. The significance and implications of these findings for UK are being widely debated.[15][16] Further studies performed in 2016 and presented at the British Cardiovascular Society Conference showed that patients admitted with a diagnosis of atrial fibrillation during the weekend had worse mortality and patients with heart failure discharged at the weekend also had a higher risk of death.[17][18]

Research led by Potluri evaluating ethnic group variations in healthcare and particularly length of stay in hospital and mortality has been widely published. His work from the ACALM Study Unit showed that patients of South Asian origin stay in hospital for a shorter period of time compared to other ethnic groups in a variety of conditions such as Myocardial Infarction, Pulmonary Embolism, Stroke, Diabetes Mellitus and Atrial Fibrillation.[19][20][21][22] Other research focusing on young South Asians has shown that they have a higher risk of Diabetes and associated heart disease compared to other ethnic groups.[21][22] In 2010, he presented research at the World Congress of Cardiology in Beijing which showed that Haemorrhagic Stroke is increasing amongst South Asians and was reported in the media.

Potluri's research from 2007 has highlighted and shown the significant effect of mental health conditions on physical health and in particular cardiovascular disease.[23][24][25] A series of publications have led to raised awareness of psychiatric conditions amongst cardiovascular disease in the UK. Specifically research showing for the first time that mental health conditions prolong length of hospital stay in patients with heart failure highlighted significant cost and service provision implications for the United Kingdom National Health Service.[23]

Another important study which was widely reported showed that married people suffering from heart attacks had significantly improved mortality and long-term survival compared to single and divorced patients.[26][27] The implications of these findings were widely debated as Marriage was thought to be a proxy for psychosocial support which is essential for heart attack sufferers to ensure they take all the prescribed medications which determines long term outcome.[28][29][30]