Serine-phosphoethanolamine synthase
In enzymology, a serine-phosphoethanolamine synthase (EC 2.7.8.4) is an enzyme that catalyzes the chemical reaction
- CDP-ethanolamine + L-serine CMP + L-serine-phosphoethanolamine
| serine-phosphoethanolamine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.8.4 | ||||||||
| CAS number | 9023-23-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are CDP-ethanolamine and L-serine, whereas its two products are CMP and L-serine-phosphoethanolamine.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-ethanolamine:L-serine ethanolamine phosphotransferase. Other names in common use include serine ethanolamine phosphate synthetase, serine ethanolamine phosphodiester synthase, serine ethanolaminephosphotransferase, serine-phosphinico-ethanolamine synthase, and serinephosphoethanolamine synthase. This enzyme participates in glycerophospholipid metabolism.
References
- Allen AK, Rosenberg H (1968). "The mechanism of action and some properties of serine ethanolamine phosphate synthetase". Biochim. Biophys. Acta. 151 (2): 504–19. doi:10.1016/0005-2744(68)90118-6. PMID 5636380.