The Man in Me

The song is featured in the soundtrack to the 1998 Coen Brothers film The Big Lebowski. It plays during the stylized opening title sequence and during the hallucination sequence after the Dude is punched and his rug stolen. More recently it has been performed live by the film's star, Jeff Bridges, at Lebowski Fest, an audience-participation oriented event commemorating the film.

The song was featured in The Simpsons episode "The Town" during a bowling montage (likely in reference to The Big Lebowski).

The song was featured in the soundtrack to the 2013 documentary The Smash Brothers, highlighting the career of Ken Hoang and paying homage to The Big Lebowski.

The song was also used in S04E17 of How I Met Your Mother.

The song is currently being used in a lighthearted ad series from Rocket Mortgage by Quicken Loans.

The song is featured in the movie "The Mauritanian" 2021 at the end of the movie with the real life main character singing it about his own story told in the movie.

In 1971, the song was covered by Lonnie Mack on his album, The Hills of Indiana. That same year, the Persuasions featured the song a capella on their album, Street Corner Symphony, and regularly in their live performances. In 1975, it was covered by London reggae band Matumbi, with another reggae version recorded by Joe Cocker the following year. The song was also covered by The Clash during sessions for the album that was to become London Calling. It is available on The Vanilla Tapes. More recently, it was covered by alternative rock group Say Anything; a demo version of the cover features Chris Conley (of Saves the Day) on vocals. The song was sampled heavily in the closing track of Blarf's 2019 album Cease & Desist, "The Me in Me." It has also been covered by Al Kooper, David Bazan (who regularly plays it live), Jenoah, Vandaveer, Buffalo Tom, and My Morning Jacket. The song was covered by Emma Swift on her 2020 album Blonde on the Tracks.