Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase

Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase (EC 2.7.8.36, PglC) is an enzyme with systematic name UDP-N,N'-diacetylbacillosamine:tritrans,heptacis-undecaprenyl-phosphate N,N'-diacetylbacillosamine transferase.[1] This enzyme catalyses the following chemical reaction

UDP-N,N'-diacetylbacillosamine + tritrans,heptacis-undecaprenyl phosphate UMP + N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase
Identifiers
EC number2.7.8.36
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from Campylobacter jejuni.

References

  1. Glover KJ, Weerapana E, Chen MM, Imperiali B (April 2006). "Direct biochemical evidence for the utilization of UDP-bacillosamine by PglC, an essential glycosyl-1-phosphate transferase in the Campylobacter jejuni N-linked glycosylation pathway". Biochemistry. 45 (16): 5343–50. doi:10.1021/bi0602056. PMID 16618123.
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