ABCG4

ATP-binding cassette sub-family G member 4 is a protein that in humans is encoded by the ABCG4 gene.[5][6]

ABCG4
Identifiers
AliasesABCG4, WHITE2, ATP binding cassette subfamily G member 4
External IDsOMIM: 607784 MGI: 1890594 HomoloGene: 75179 GeneCards: ABCG4
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q23.3Start119,149,052 bp[1]
End119,162,653 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

64137

192663

Ensembl

ENSG00000172350

ENSMUSG00000032131

UniProt

Q9H172

n/a

RefSeq (mRNA)

NM_001142505
NM_022169
NM_001348191
NM_001348192

NM_138955

RefSeq (protein)

NP_001135977
NP_071452
NP_001335120
NP_001335121

n/a

Location (UCSC)Chr 11: 119.15 – 119.16 MbChr 9: 44.27 – 44.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is included in the ATP-binding cassette transporter (ABC protein) superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.[6]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000172350 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032131 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Dean M, Rzhetsky A, Allikmets R (Jul 2001). "The human ATP-binding cassette (ABC) transporter superfamily". Genome Res. 11 (7): 1156–66. doi:10.1101/gr.184901 (inactive 2021-01-14). PMID 11435397.CS1 maint: DOI inactive as of January 2021 (link)
  6. "Entrez Gene: ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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