CSF albumin

CSF albumin is a measurement used to determine the levels of albumin in cerebrospinal fluid.[1]

CSF albumin
LOINC1746-7 (MCnc)
2861-3 (MCnc, electrophoresis)
43711-1 (ACnc)

A closely related test, CSF total protein is a measurement used to determine the levels of protein in cerebrospinal fluid.[2][3] It combines the albumin, IgG, and other proteins.

It can be useful in distinguishing among causes of Meningitis. It is more likely to be elevated in bacterial meningitis than in viral meningitis.

The upper normal range is 150 mg/dl in neonates, and 50 mg/dl in adults.[4]

Pathophysiology sample values
BMP/ELECTROLYTES:
Na+ = 140 Cl− = 100 BUN = 20 /
Glu = 150
K+ = 4 CO2 = 22 PCr = 1.0 \
ARTERIAL BLOOD GAS:
HCO3− = 24 paCO2 = 40 paO2 = 95 pH = 7.40
ALVEOLAR GAS:
pACO2 = 36 pAO2 = 105 A-a g = 10
OTHER:
Ca = 9.5 Mg2+ = 2.0 PO4 = 1
CK = 55 BE = −0.36 AG = 16
SERUM OSMOLARITY/RENAL:
PMO = 300 PCO = 295 POG = 5 BUN:Cr = 20
URINALYSIS:
UNa+ = 80 UCl− = 100 UAG = 5 FENa = 0.95
UK+ = 25 USG = 1.01 UCr = 60 UO = 800
PROTEIN/GI/LIVER FUNCTION TESTS:
LDH = 100 TP = 7.6 AST = 25 TBIL = 0.7
ALP = 71 Alb = 4.0 ALT = 40 BC = 0.5
AST/ALT = 0.6 BU = 0.2
AF alb = 3.0 SAAG = 1.0 SOG = 60
CSF:
CSF alb = 30 CSF glu = 60 CSF/S alb = 7.5 CSF/S glu = 0.4

References
  1. Murakami K, Nakagawa T, Shozu M, Uchide K, Koike K, Inoue M (September 1999). "Changes with aging of steroidal levels in the cerebrospinal fluid of women". Maturitas. 33 (1): 71–80. doi:10.1016/S0378-5122(99)00040-7. PMID 10585175.
  2. "MedlinePlus Medical Encyclopedia: CSF total protein".
  3. Seehusen DA, Reeves MM, Fomin DA (September 2003). "Cerebrospinal fluid analysis". Am Fam Physician. 68 (6): 1103–8. PMID 14524396.
  4. Karen Roos (2005). Principles of neurologic infectious diseases. New York: McGraw-Hill, Medical Pub. Division. p. 4. ISBN 0-07-140816-9.


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