Cefsulodin

Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by Takeda Pharmaceutical Company in 1977.[1]

Cefsulodin
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Chemical and physical data
FormulaC22H21N4O8S2+
Molar mass533.55 g·mol−1
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TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985.[2]

Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms.[3] This agar is most often used in water and beverage testing.

Susceptibility data

The following represents MIC susceptibility data for various P. aeruginosa strains:[4]

  • Pseudomonas aeruginosa PA13 (resistant strain): 32 μg/ml
  • Pseudomonas aeruginosa (wild-type, susceptible): 4 - 8 μg/ml

References

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