Colorado State Highway 340

The route begins at a concurrency of US 6 and US 50 in Fruita. The route then turns onto cherry Street in Fruita where it junctions with Interstate 70 (I-70). The Highway then moves then heads south, passing over the Colorado River, where it heads into The Redlands. There, it traverses the suburban area as Broadway Rd, passing the Colorado National Monument on the south side of the highway. As SH 340 travels eastward, it enters Downtown Grand Junction, meeting again with the Colorado River and passing over the Riverside Parkway. Then, the highway ends at I-70 Bus. and US 50.

The route was defined in 1939, when it moved along its current alignment but continued to US 6 in Palisade. This entire length was paved by 1955. The east terminus was then moved to SH 146, today's SH 141, in 1970. Two years later, the east terminus was moved all the way to where it is now in Grand Junction.[2]

The entire route is in Mesa County.

Location	mi	km	Destinations	Notes
Fruita	0.000	0.000	US 6 / US 50	Western terminus
	0.507	0.816	I-70	I-70 exit 19; interchange
Grand Junction	13	21	Riverside Parkway	Interchange; Eastbound exit only
	13.341	21.470	I-70 BL / US 50	Eastern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus             Incomplete access       Route transition