Iotroxic acid

Iotroxic acid, also known as meglumine iotroxate, is a molecule used as a contrast medium during X-rays.[1][2] It is specifically used during tests looking at the gallbladder and biliary tract.[2] It is given by slow injection into a vein.[2]

Iotroxic acid
Clinical data
Trade namesBiliscopin, others
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.051.726
Chemical and physical data
FormulaC22H18I6N2O9
Molar mass1215.818 g·mol−1
3D model (JSmol)

Side effects are uncommon.[3] They include vomiting, skin flushing, headache, itchiness, and low blood pressure.[2] Rare side effects include seizures and allergic reactions.[2] It should not be used by those who have an iodine allergy.[2] Iotroxic acid is an iodine containing contrast media of the diionic dimer type.[4]

Iotroxic acid was first made in 1976.[5] It is on the World Health Organization's List of Essential Medicines.[6] It is rarely used in the developed world due to the availability of magnetic resonance cholangiopancreatography (MRCP).[7]

References
  1. "Iotroxic Acid - Drugs.com". www.drugs.com. Archived from the original on 31 December 2016. Retrieved 31 December 2016.
  2. World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 315, 318. hdl:10665/44053. ISBN 9789241547659.
  3. Neugebauer, Edmund; Sauerland, Stefan (2014). Recommendations for evidence-based endoscopic surgery: The updated EAES consensus development conferences. Springer Science & Business Media. p. 67. ISBN 9782817808499. Archived from the original on 2017-01-01.
  4. Schaefer, Christof; Peters, Paul W. J.; Miller, Richard K. (2014). Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. Academic Press. p. 532. ISBN 9780124079014. Archived from the original on 2017-01-01.
  5. Korolkovas, Andrejus (1988). Essentials of Medicinal Chemistry. Wiley. p. 1063. ISBN 9780471883562. Archived from the original on 2017-01-01.
  6. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  7. Sherlock, Shiela; Dooley, James (2008). Diseases of the Liver and Biliary System. John Wiley & Sons. p. 568. ISBN 9780470986813. Archived from the original on 2017-01-01.
  • "Iotroxic Acid". Drug Information Portal. U.S. National Library of Medicine.
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