Neuralink

Neuralink Corporation is a neurotechnology company founded by Elon Musk and others, developing implantable brain–machine interfaces (BMIs). The company's headquarters are in San Francisco;[6] it was started in 2016 and was first publicly reported in March 2017.[1][2]

Neuralink Corporation
TypePrivate
IndustryBrain-computer interface
Neuroprosthetics
FoundedJuly 2016 (2016-07)[1]
FounderElon Musk[2][3]
HeadquartersPioneer Building, San Francisco, California, U.S. (as of 2020)[4]
Key people
  • Max Hodak (President)
  • Elon Musk (CEO)
OwnerElon Musk
Number of employees
Around 100[5] (08/2020)
Websiteneuralink.com

Since its founding, the company has hired several high-profile neuroscientists from various universities.[7] By July 2019, it had received $158 million in funding (of which $100 million was from Musk) and was employing a staff of 90 employees.[8] At that time, Neuralink announced that it was working on a "sewing machine-like" device capable of implanting very thin (4 to 6 μm in width[9]) threads into the brain, and demonstrated a system that read information from a lab rat via 1,500 electrodes, they had anticipated starting experiments with humans in 2020;[8] but have since moved that projection to 2021.[10]

Some claims made by Musk in relation to the technology have been criticized by several neuroscientists and publications, including the MIT Technology Review.[11][12]

Overview

The Pioneer Building in San Francisco, housing the offices of Neuralink and OpenAI

Neuralink was founded in 2016 by Elon Musk and eight partners; Ben Rapoport, Dongjin Seo, Max Hodak, Paul Merolla, Philip Saps, Tim Gardner, Tim Hanson and Vanessa Tolosa, a group of experts in different areas. (see #Members)[6]

In April 2017, the blog Wait But Why reported that the company was aiming to make devices to treat serious brain diseases in the short-term, with the eventual goal of human enhancement, sometimes called transhumanism.[13][6][14] Musk said his interest in the idea partly stemmed from the science fiction concept of "neural lace" in the fictional universe in The Culture, a series of 10 novels by Iain M. Banks.[14][15]

Musk defined the neural lace as a "digital layer above the cortex" that would not necessarily imply extensive surgical insertion but ideally an implant through a vein or artery.[16] Musk explained that the long-term goal is to achieve "symbiosis with artificial intelligence",[17] which he perceives as an existential threat to humanity if it goes unchecked.[17][18] As of 2017, some neuroprosthetics can interpret brain signals and allow disabled people to control their prosthetic arms and legs. Musk spoke of aiming to link that technology with implants that, instead of actuating movement, can interface at broadband speed with other types of external software and gadgets.[18]

As of 2020, Neuralink is headquartered in San Francisco's Mission District, sharing the former Pioneer Trunk Factory building with OpenAI, another company co-founded by Musk.[19][4] Musk was the majority owner of Neuralink as of September 2018, but did not hold an executive position.[20] Jared Birchall was listed as CEO, CFO and president of Neuralink in 2018; his role has been described as formal.[21][19] An August 2020 tweet confirmed past reports that Musk is the current CEO.[22] The trademark "Neuralink" was purchased from its previous owners in January 2017.[23]

Members

The company is made up of a group of experts in different areas such as neuroscience, biochemistry, robotics, applied mathematics, machinery, among others. It is currently looking for experts in different scientific areas to shape his team.[24]

Its founding members are:

  • Elon Musk.
  • Max Hodak, president of the company. He previously worked on the development of brain-computer interfaces at Duke University.[25]
  • Matthew McDougall, Head of Neurosurgery at Neuralink and neurosurgeon at California Pacific Medical Center. He was previously working at Stanford where he worked in labs that implemented and designed brain-computer interfaces.
  • Vanessa Tolosa, Director of Neural Interfaces. She previously led a neurotechnology team at the Lawrence Livermore National Laboratory that worked with a wide variety of technology on technology prostheses that were used in clinical and academic settings.
  • DJ Seo, director of the Implantation System. He was the co-inventor of "neural dust" a technology he developed while studying at UC Berkeley.
  • Philip Sabes, senior scientist. He was a professor of physiology at UC San Francisco and led a lab that studied how the brain processed sensorial and motor signals.
  • Tim Gardner, professor of biology at Boston University, in which they have worked on the implementation of brain-computer interfaces in birds.
  • Ben Rapoport, neurosurgeon with a PhD in electrical engineering and computer science from MIT.
  • Tim Hanson, researcher at the Berkeley Sensor and Acuator Center.

By August 2020, only three of the eight founding scientists remained at the company, according to an article by Stat News which reported that Neuralink had seen "years of internal conflict in which rushed timelines have clashed with the slow and incremental pace of science."[26]

Technology

By 2018, the company had "remained highly secretive about its work since its launch", although public records showed that it had sought to open an animal testing facility in San Francisco; it subsequently started to carry out research at the University of California, Davis.[19] In 2019, during a live presentation at the California Academy of Sciences, the Neuralink team revealed to the public the technology of the first prototype they had been working on. It is a system that involves ultra-thin probes that will be inserted into the brain, a neurosurgical robot that will perform the operations and a high-density electronic system capable of processing information from neurons.

Probes

The probes, composed mostly of polyamide, a biocompatible material, and coated in a thin gold thread, will be inserted into the brain through an automated process performed by a surgical robot.

Each probe consists of an area of wires that contains electrodes capable of locating electrical signals in the brain, and a sensory area where the wire interacts with an electronic system that allows amplification and acquisition of the brain signal.

Each of the probes contains 48 or 96 wires, each of which contains 32 independent electrodes; achieving this way a system of up to 3072 electrodes per formation.[9][27]

Robot

Studies involving the insertion of probes in the brain have shown that, due to their rigidity, the body recognizes them as an unknown material and, consequently, generates tissue to get rid of them, which, in turn, long term, makes them unusable.[28]

For this reason, Neuralink has developed a robot capable of inserting flexible probes, allowing the rapid insertion of multiples of these to minimize trauma that can trigger a bounce reaction.[29][30]

This robot has an insertion head with a 40 μm diameter needle made of tungsten-rhenium designed to attach to the insertion loops, made to transport and insert individual probes, and to penetrate the meninges and tissue cerebral. The robot is capable of inserting up to six probes (192 electrodes) per minute.[29]

Electronics

Elon Musk discussing the Neuralink

Neuralink has developed an Application-Specific Integrated Circuit (ASIC) to create a 1,536-channel recording system.

This system consists of 256 amplifiers capable of being individually programmed ("analog pixels"), analog-to-chip converters within the chip ("ADCs") and a peripheral circuit control to serialize the digitized information obtained.[29]

It aims to convert information obtained from neurons into an understandable binary code in order to achieve greater understanding of brain function and the ability to stimulate these neurons back.

Currently, electrodes are still too big to record the firing of individual neurons, so they can record only the firing of a group of neurons; Neuralink representatives believe this issue might get mitigated algorithmically, but it's computationally expensive and does not produce exact results.[31]

In July 2020, according to Musk, Neuralink obtained a FDA breakthrough device designation which allows limited human testing under the FDA guidelines for medical devices.[32][33]

Reception

Several neurology scientists have commented on the intention of Musk and members of Neuralink to build a brain-computer interface.[34] The response from the scientific community has been mixed.

At a live demonstration in August 2020, Musk described one of their early devices as "a Fitbit in your skull" which could soon cure paralysis, deafness, blindness, and other disabilities. Many neuroscientists and publications criticized these claims.[11][12][35] For example, MIT Technology Review described them as "highly speculative" and "neuroscience theater".[11]

Mary Lou Jepsen, founder of Openwater, a company that also works in the area of brain-computer interfaces, with the goal of creating a telepathy system, has expressed concern about the rejection reactions that probes can cause.

Thomas Oxley, MD, PhD, CEO of Synchron, an Australian company that is also developing a system to insert brain probes via blood-vessel-borne catheters that avoid any direct penetration with brain tissue, and therefore do not cause trauma, says no efficacy results from Neuralink are expected soon, as the technology is not advanced enough to achieve this. However, he believes that because Musk is willing to invest large sums of money in his company, it will be "exciting to see what he will develop."

Criticism

Neuralink tests their devices by surgically implanting them in the brains of live monkeys, pigs and other animals.[36] These methods have been criticized by groups such as PETA.[37]

See also

References

  1. Winkler, Rolfe (March 27, 2017). "Elon Musk Launches Neuralink to Connect Brains With Computers". Wall Street Journal. Archived from the original on May 5, 2017. Retrieved May 4, 2017.
  2. Statt, Nick (March 27, 2017). "Elon Musk launches Neuralink, a venture to merge the human brain with AI". The Verge. Archived from the original on February 6, 2018. Retrieved September 6, 2017.
  3. 5 Neuroscience Experts Weigh in on Elon Musk's Mysterious "Neural Lace" Company Archived December 31, 2018, at the Wayback Machine. (PDF) Eliza Strickland. Harvard University. 12 April 2017.
  4. Hao, Karen (February 17, 2020). "The messy, secretive reality behind OpenAI's bid to save the world". MIT Technology Review. Retrieved March 9, 2020.
  5. "Neuralink Progress Update, Summer 2020". Youtube. Neuralink. Retrieved August 29, 2020.
  6. Masunaga, Samantha (April 21, 2017). "A quick guide to Elon Musk's new brain-implant company, Neuralink". Los Angeles Times. Archived from the original on May 5, 2017. Retrieved May 4, 2017.
  7. "Elon Musk's Brain Tech Startup Is Raising More Cash". May 11, 2019. Archived from the original on May 11, 2019. Retrieved May 12, 2019. The company has hired away several high-profile neuroscientists
  8. Markoff, John (July 16, 2019). "Elon Musk's Company Takes Baby Steps to Wiring Brains to the Internet". The New York Times. ISSN 0362-4331. Archived from the original on July 17, 2019. Retrieved July 17, 2019.
  9. Elon Musk unveils Neuralink’s plans for brain-reading ‘threads’ and a robot to insert them. Archived July 17, 2019, at the Wayback Machine Elizabeth Lopatto, The Verge. 16 July 2019.
  10. Español, Entrepreneur en (February 4, 2021). "Neuralink Could Begin Testing Human Brain Implants This Year, Says Elon Musk". Entrepreneur. Retrieved February 6, 2021.
  11. Regalado, Antonio (August 30, 2020). "Elon Musk's Neuralink is neuroscience theater". MIT Technology Review. Retrieved September 3, 2020.
  12. Cellan-Jones, Rory (September 1, 2020). "Is Elon Musk over-hyping his brain-hacking Neuralink tech?". BBC News. Archived from the original on September 12, 2020. Retrieved September 14, 2020.
  13. Urban, Tim (April 20, 2017). "Neuralink and the Brain's Magical Future". Wait But Why. Archived from the original on May 4, 2017. Retrieved May 4, 2017.
  14. Newitz, Annalee (March 27, 2017). "Elon Musk is setting up a company that will link brains and computers". Ars Technica. Archived from the original on May 19, 2017. Retrieved May 4, 2017.
  15. Cross, Tim (March 31, 2017). "The novelist who inspired Elon Musk". 1843 Magazine. Archived from the original on May 21, 2017. Retrieved May 4, 2017.
  16. Elon Musk thinks we will have to use AI this way to avoid a catastrophic future Archived February 13, 2019, at the Wayback Machine. Robert Ferris, CNBC News. 31 January 2017.
  17. Elon Musk believes AI could turn humans into an endangered species like the mountain gorilla Archived December 4, 2018, at the Wayback Machine. Isobel Asher Hamilton, Business Insider. 26 November 2018.
  18. Everything you need to know about Neuralink: Elon Musk’s brainy new venture Archived December 6, 2018, at the Wayback Machine. Tyler Lacoma, Digital Trends. 7 November 2017.
  19. Conger, Kate. "Elon Musk's Neuralink Sought to Open an Animal Testing Facility in San Francisco". Gizmodo. Archived from the original on September 24, 2018. Retrieved October 11, 2018.
  20. No-Action Letter: Neuralink Corp Archived July 20, 2019, at the Wayback Machine. U.S. Securities and Exchange Commission (SEC), October 16, 2018
  21. Oremus, April Glaser, Aaron Mak, Will (August 17, 2018). "Why Elon Musk's Companies Aren't Melting Down, Even If He Is". Slate Magazine. Archived from the original on July 20, 2019. Retrieved July 20, 2019.
  22. @max_hodak (August 27, 2020). "Elon is the CEO" (Tweet) via Twitter.
  23. Meet the Guys Who Sold "Neuralink" to Elon Musk without Even Realizing It, April 4, 2017, MIT Technology Review
  24. "Neuralink jobs". jobs.lever.co. Retrieved October 26, 2019.
  25. Samantha, Masunaga (April 21, 2017). "A quick guide to Elon Musk's new brain-implant company, Neuralink". Los Angeles Times.
  26. "Ahead of Neuralink event, ex-employees detail research timeline clashes". STAT. August 25, 2020. Retrieved September 6, 2020.
  27. Elon Musk’s Neuralink Aims to Merge Human Brain With A.I. Archived July 29, 2019, at the Wayback Machine Dinker, TechBrackets. 18 July 2019.
  28. Biran, Roy; Martin, David C.; Tresco, Patrick A. (September 1, 2005). "Neuronal cell loss accompanies the brain tissue response to chronically implanted silicon microelectrode arrays". Experimental Neurology. 195 (1): 115–126. doi:10.1016/j.expneurol.2005.04.020. ISSN 0014-4886.
  29. Musk, Elon; Neuralink (July 18, 2019). "An integrated brain-machine interface platform with thousands of channels". bioRxiv: 703801. doi:10.1101/703801.
  30. Hanson, Timothy L.; Diaz-Botia, Camilo A.; Kharazia, Viktor; Maharbiz, Michel M.; Sabes, Philip N. (March 14, 2019). "The "sewing machine" for minimally invasive neural recording". bioRxiv: 578542. doi:10.1101/578542.
  31. "Neuralink Paper Review - Numenta Research Meeting". Numenta, Inc. Archived from the original on July 24, 2019. Retrieved July 27, 2019 via YouTube.
  32. Metz, Rachel (August 28, 2020). "Elon Musk shows off a working brain implant — in pigs". CNN. Retrieved October 4, 2020.
  33. Neuralink Progress Update, Summer 2020, Neuralink, 28 August 2020, accessed 4 October 2020.
  34. "Full Page Reload". IEEE Spectrum: Technology, Engineering, and Science News. Retrieved October 26, 2019.
  35. Rogers, Adam (September 4, 2020). "Neuralink Is Impressive Tech, Wrapped in Musk Hype". Wired. Archived from the original on September 7, 2020. Retrieved September 14, 2020.
  36. Shead, Sam (February 1, 2021). "Elon Musk says his start-up Neuralink has wired up a monkey to play video games using its mind". CNBC. Retrieved February 1, 2021.
  37. Linder, Courtney (September 9, 2020). "Why Is Elon Musk Testing His Brain Implant on Pigs?". Popular Mechanics. Retrieved January 26, 2021.

Further reading

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