Ozolinone

Ozolinone
Clinical data
Routes of; administration	Oral
ATC code	None;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name (2Z)-2-(3-methyl-4-oxo-5-piperidin-1-yl-1,3-thiazolidin-2-ylidene)acetic acid;
CAS Number	56784-39-5;
PubChem CID	6436036;
ChemSpider	23253355;
UNII	55TIT7J81D;
KEGG	D05323;
ECHA InfoCard	100.054.876
Chemical and physical data
Formula	C11H16N2O3S
Molar mass	256.32 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)/C=C1/N(C)C(=O)C(S1)N2CCCCC2;

Ozolinone is a loop diuretic which was never marketed.[1][2][3]

References

Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8.
Greven J, Heidenreich O (October 1978). "Effects of ozolinone, a diuretic active metabolite of etozoline, on renal function. I. Clearance studies in dogs". Naunyn-Schmiedeberg's Archives of Pharmacology. 304 (3): 283–7. doi:10.1007/bf00507970. PMID 714186. S2CID 20878253.
Greven J, Beckers M, Defrain W, Meywald K, Heidenreich O (March 1980). "Studies with the optically active isomers of the new diuretic drug ozolinone. II. Inhibition by d-ozolinone of furosemide-induced diuresis". Pflügers Archiv : European Journal of Physiology. 384 (1): 61–4. doi:10.1007/bf00589515. PMID 7189867. S2CID 13461213.

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