Rousettus bat coronavirus HKU9
Rousettus bat coronavirus HKU9 (HKU9-1) is an enveloped, positive-sense, single-stranded RNA mammalian Group 2 Betacoronavirus discovered in Rousettus bats in China in 2011. This strain of coronavirus is closely related to the EMC/2012 strain found in London which is related to the Middle East respiratory syndrome-related coronavirus (MERS-CoV). The MERS-CoV species is responsible for the 2012 Middle East respiratory syndrome coronavirus outbreak in Saudi Arabia, Jordan, United Arab Emirates, the United Kingdom, France, and Italy.[1][2][3]
Rousettus bat coronavirus HKU9 | |
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Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Pisuviricota |
Class: | Pisoniviricetes |
Order: | Nidovirales |
Family: | Coronaviridae |
Genus: | Betacoronavirus |
Subgenus: | Nobecovirus |
Species: | Rousettus bat coronavirus HKU9 |
Transmission
The exact means of transmission to humans is not yet well known. However, it has been demonstrated that betaCoV's including HKU4 have the propensity to recombine and cause interspecies transmission. However, this is not seen in Group C betaCov's to which MERS-CoV is most closely related.[4]
See also
References
- Lau, Susanna K. P.; Poon, Rosana W. S.; Wong, Beatrice H. L.; Wang, Ming; Huang, Yi; Xu, Huifang; Guo, Rongtong; Li, Kenneth S. M.; Gao, Kai; Chan, Kwok-Hung; Zheng, Bo-Jian (2010-11-01). "Coexistence of Different Genotypes in the Same Bat and Serological Characterization of Rousettus Bat Coronavirus HKU9 Belonging to a Novel Betacoronavirus Subgroup". Journal of Virology. 84 (21): 11385–11394. doi:10.1128/JVI.01121-10. ISSN 0022-538X. PMC 2953156. PMID 20702646.
- Yang, Li; Wu, Zhiqiang; Ren, Xianwen; Yang, Fan; He, Guimei; Zhang, Junpeng; Dong, Jie; Sun, Lilian; Zhu, Yafang; Du, Jiang; Zhang, Shuyi (June 2013). "Novel SARS-like Betacoronaviruses in Bats, China, 2011". Emerging Infectious Diseases. 19 (6). doi:10.3201/eid1906.121648. ISSN 1080-6040. PMC 3713832. PMID 23739658.
- Annan, Augustina; Baldwin, Heather J.; Corman, Victor Max; Klose, Stefan M.; Owusu, Michael; Nkrumah, Evans Ewald; Badu, Ebenezer Kofi; Anti, Priscilla; Agbenyega, Olivia; Meyer, Benjamin; Oppong, Samuel (March 2013). "Human Betacoronavirus 2c EMC/2012–related Viruses in Bats, Ghana and Europe". Emerging Infectious Diseases. 19 (3): 456–459. doi:10.3201/eid1903.121503. ISSN 1080-6040. PMC 3647674. PMID 23622767.
- Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708.