U.C. Sampdoria in European football

The Genoese club have won one continental title: the Cup Winners' Cup in 1990, overcoming Anderlecht in Gothenburg.

This victory came during the greatest period of success in the history of the club, largely under coach Vujadin Boškov and featuring players such as Pagliuca, Mancini, Vialli, Vierchowod and Lombardo. In the 1988–89 Cup Winners' Cup they had finished runners-up to FC Barcelona in the Bern final, but in the same season won the Coppa Italia (one of four domestic cup wins from six finals in nine years), allowing another opportunity to compete for the European prize, which they duly achieved the following year. In the 1994–95 edition of the same tournament, Samp reached the semi-final before being eliminated on penalties by Arsenal.

In addition, Sampdoria won their only Serie A national title in 1991, and in the subsequent European Cup campaign they went all the way to the final in London, again facing Barcelona and losing by a single goal late in extra time. It was the last year before that competition became known as the Champions League, although its format did involve a group stage.

Since the mid-1990s, the club's European involvement has been less frequent and less prominent, although they have participated in the group stages of the UEFA Cup / Europa League on three occasions in the early 21st century (failing to progress each time).

Sampdoria's score listed first.

European Cup/Champions League

Season	Round	Club	Home	Away	Aggregate	Reference
1991–92	First round	Rosenborg	5–0	2–1	7–1	[2]
	Second round	Budapest Honvéd	3–1	1–2	4–3
	Group A	Red Star Belgrade	2–0	3–1	1st
		Panathinaikos	1–1	0–0
		Anderlecht	2–0	2–3
	Final	Barcelona	0–1 (a.e.t.) (N)
2010–11	Play-off round	Werder Bremen	3–2 (a.e.t.)	1–3	4–5	[3]

European Cup Winners' Cup/UEFA Cup Winners' Cup

Season	Round	Club	Home	Away	Aggregate	Reference
1985–86	First round	AEL 1964	1–0	1–1	2–1	[4]
	Second round	Benfica	1–0	0–2	1–2
1988–89	First round	Norrköping	2–0	1–2	3–2	[5]
	Second round	Carl Zeiss Jena	3–1	1–1	4–2
	Quarter-finals	Dinamo București	0–0	1–1	1–1 (a)
	Semi-finals	Mechelen	3–0	1–2	4–2
	Final	Barcelona	0–2 (N)
1989–90	First round	Brann	1–0	2–0	3–0	[6]
	Second round	Borussia Dortmund	2–0	1–1	3–1
	Quarter-finals	Grasshopper	2–0	2–1	4–1
	Semi-finals	Monaco	2–0	2–2	4–2
	Final	Anderlecht	2–0 (a.e.t.) (N)
1990–91	First round	Kaiserslautern	2–0	0–1	2–1	[7]
	Second round	Olympiacos	3–1	1–0	4–1
	Quarter-finals	Legia Warsaw	2–2	0–1	2–3
1994–95	First round	Bodø/Glimt	2–0	2–3	4–3	[8]
	Second round	Grasshopper	3–0	2–3	5–3
	Quarter-finals	Porto	0–1	1–0	1–1, 5–3 (p)
	Semi-finals	Arsenal	3–2	2–3	5–5, 2–3 (p)

UEFA Cup/Europa League

Season	Round	Club	Home	Away	Aggregate	Reference
1997–98	First round	Athletic Bilbao	1–2	0–2	1–4	[9]
2005–06	First round	Vitória de Setúbal	1–0	1–1	2–1	[10]
	Group C	Steaua București	0–0	N/A	4th
		Halmstad	N/A	3–1
		Hertha BSC	0–0	N/A
		Lens	N/A	1–2
2007–08	Second qualifying round	Hajduk Split	1–1	1–0	2–1	[11]
	First round	Aalborg BK	2–2	0–0	2–2 (a)
2008–09	First round	Kaunas	5–0	2–1	7–1	[12]
	Group C	Partizan	N/A	2–1	3rd
		Stuttgart	1–1	N/A
		Standard Liège	N/A	0–3
		Sevilla	1–0	N/A
	Round of 32	Metalist Kharkiv	0–1	0–2	0–3
2010–11	Group I	PSV Eindhoven	1–2	1–1	3rd	[13]
		Debrecen	1–0	0–2
		Metalist Kharkiv	0–0	1–2
2015–16	Third qualifying round	Vojvodina	0–4	2–0	2–4	[14]

UEFA Intertoto Cup

Season	Round	Club	Home	Away	Aggregate	Reference
1998	Second round	Rimavská Sobota	2–0	0–1	2–1	[15]
	Third round	Harelbeke	3–0	1–0	4–0
	Semi-finals	Bologna	1–0	1–3	2–3
2007	Third round	Cherno More Varna	1–0	1–0	2–0	[16]

European Super Cup

Season	Club	Home	Away	Aggregate	Reference
1990	Milan	1–1	0–2	1–3	[17][18]