1981 NFL season

The 1981 NFL Draft was held from April 28 to 29, 1981 at New York City’s Sheraton Hotel. With the first pick, the New Orleans Saints selected running back George Rogers from the University of South Carolina.

Cal Lepore, the line judge for Super Bowl III and referee for the Miracle at the Meadowlands, retired prior to the 1980 season. He would later become supervisor of officials in the United States Football League. Tom Dooley, who was assigned Super Bowl XV as line judge at the end of the 1981 season, was promoted to referee to replace Lepore.

• It is illegal for any player to put adhesive or slippery substances such as the product “stickum” on his body, equipment or uniform. This rule is known as both the “Lester Hayes Rule” and the “Fred Biletnikoff Rule” since both players were notorious for using sticky substances to make it easier for them to intercept/catch passes.
• An offensive player who comes into the game wearing an illegal number for the position he takes must report to the referee before the start of the next play.
• The penalty for an ineligible receiver who touches a forward pass is a loss of down.
• The penalty for illegal use of hands, arms, or body (including holding) is reduced from 15 yards to 10 yards.
• The penalty for intentional grounding is modified: loss of down and 10 yards penalty from the previous spot, or if the foul occurs more than 10 yards from the line of scrimmage, loss of down at the spot of the foul.
• Officials began wearing numbers 21 through 25 within their position groups after going no higher than number 20 in 1979 and 1980.

* Indicates overtime victory

• Denver Broncos: Dan Reeves replaced the fired Red Miller.
• Houston Oilers: Bum Phillips was fired and replaced by Ed Biles.
• New Orleans Saints: Bum Phillips joined the Saints after being fired by the Oilers. Dick Nolan was fired after a 0–12 start in 1980, and Dick Stanfel took over as interim.
• Washington Redskins: Joe Gibbs replaced Jack Pardee.

The home of the San Diego Chargers, San Diego Stadium, was renamed Jack Murphy Stadium in memory of local sportswriter Jack Murphy

• The Cincinnati Bengals made significant modifications to their uniforms for the first time since the team's debut in 1968, discontinuing the design similar to the Cleveland Browns' jerseys. Orange and black tiger stripes were added to the jerseys and pants. Black tiger stripes were also added to the orange helmets.
• The Dallas Cowboys adopted a new blue jersey which was darker than its predecessors and featured silver numbers. The Cowboys wore this blue jersey through 1994.
• The Houston Oilers resumed wearing blue pants with their white jerseys.

• NFL Record and Fact Book (ISBN 1-932994-36-X)
• NFL History 1981–1990 (Last accessed December 4, 2005)
• Total Football: The Official Encyclopedia of the National Football League (ISBN 0-06-270174-6)