5''-phosphoribostamycin phosphatase
5''-phosphoribostamycin phosphatase (EC 3.1.3.88, btrP (gene), neoI (gene)) is an enzyme with systematic name 5-phosphoribostamycin phosphohydrolase.[1] This enzyme catalyses the following chemical reaction
- 5-phosphoribostamycin + H2O ribostamycin + phosphate
5''-phosphoribostamycin phosphatase | |||||||||
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Identifiers | |||||||||
EC number | 3.1.3.88 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This enzyme is involved in the biosynthesis of several aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin.
References
- Kudo F, Fujii T, Kinoshita S, Eguchi T (July 2007). "Unique O-ribosylation in the biosynthesis of butirosin". Bioorganic & Medicinal Chemistry. 15 (13): 4360–8. doi:10.1016/j.bmc.2007.04.040. PMID 17482823.
External links
- -phosphoribostamycin%20phosphatase 5-phosphoribostamycin+phosphatase at the US National Library of Medicine Medical Subject Headings (MeSH)
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