CNTROB

Centrobin is a protein that in humans is encoded by the CNTROB gene.[5] It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.[6]

CNTROB
Identifiers
AliasesCNTROB, LIP8, PP1221, centrobin, centriole duplication and spindle assembly protein
External IDsOMIM: 611425 MGI: 2443290 HomoloGene: 14205 GeneCards: CNTROB
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17p13.1Start7,932,101 bp[1]
End7,949,920 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

116840

216846

Ensembl

ENSG00000170037

ENSMUSG00000032782

UniProt

Q8N137

Q8CB62

RefSeq (mRNA)

NM_172560

RefSeq (protein)

NP_766148

Location (UCSC)Chr 17: 7.93 – 7.95 MbChr 11: 69.3 – 69.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000170037 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032782 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Tchernev, V. T.; Mansfield, T. A.; Giot, L.; Kumar, A. M.; Nandabalan, K.; Li, Y.; Mishra, V. S.; Detter, J. C.; Rothberg, J. M.; Wallace, M. R.; Southwick, F. S.; Kingsmore, S. F. (2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Molecular Medicine (Cambridge, Massachusetts). 8 (1): 56–64. doi:10.1007/bf03402003. PMC 2039936. PMID 11984006.
  6. Zou, C.; Li, J.; Bai, Y.; Gunning, W.; Wazer, D.; Band, V.; Gao, Q. (2005). "Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication". Journal of Cell Biology. 171 (3): 437–445. doi:10.1083/jcb.200506185. PMC 2171251. PMID 16275750.

Further reading


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