Chlorantraniliprole

Chlorantraniliprole (Rynaxypyr) is an insecticide of the ryanoid class.[1] Chlorantraniliprole is being developed world-wide by DuPont belonging to a new class of selective insecticides featuring a novel mode of action to control a range of pests belonging to the order Lepidoptera and some other Coleoptera, Diptera and Isoptera species.

Chlorantraniliprole

Chlorantraniliprole 3D molecular model generated using Avogadro software
Names
IUPAC name 5-bromo-N-[4-chloro-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloropyridin-2-yl)pyrazole-3-carboxamide
Other names Rynaxpyr
Identifiers
CAS Number	500008-45-7
3D model (JSmol)	Interactive image
ChEBI	CHEBI:67113
ChEMBL	ChEMBL399318
ECHA InfoCard	100.112.607
EC Number	610-489-8
KEGG	C18454
PubChem CID	11271640
UNII	622AK9DH9G
CompTox Dashboard (EPA)	DTXSID2044345
InChI InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) Key: PSOVNZZNOMJUBI-UHFFFAOYSA-N
SMILES CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br
Properties
Chemical formula	C18H14BrCl2N5O2
Molar mass	483.15 g·mol−1
Hazards
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H319, H335, H400, H410
GHS precautionary statements	P261, P264, P271, P273, P280, P304+340, P305+351+338, P312, P337+313, P391, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Chlorantraniliprole opens muscular calcium channels (in particular the ryanodine receptor), rapidly causing paralysis and ultimately death of sensitive species. The differential selectivity Chlorantraniliprole had towards insect ryanodine receptors explained the outstanding profile of low mammalian toxicity. Chlorantraniliprole is active on chewing pest insects primarily by ingestion and secondarily by contact.

As active ingredient (a.i.) in insecticide -

a. Chlorantraniliprole 0.4% GR having the trade name Ferterra.

b. Chlorantraniliprole 18.5% SC having the trade name Coragen.