Clofibride
Clofibride is a fibrate. Clofibride is a derivative of clofibrate. In the body it is converted into 4-chlorophenoxyisobutyric acid (clofibric acid),[1] which is the true hypolipidemic agent.[2] So clofibride, just like clofibrate is a prodrug of clofibric acid.
 | |
| Clinical data | |
|---|---|
| ATC code | |
| Pharmacokinetic data | |
| Metabolism | Hydrolyzed to clofibric acid; hepatic glucuronidation |
| Elimination half-life | 12 hours (clofibric acid) |
| Excretion | Renal (mostly) and fecal |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.043.542  |
| Chemical and physical data | |
| Formula | C16H22ClNO4 |
| Molar mass | 327.81 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
| (verify) | |
References
- https://pubchem.ncbi.nlm.nih.gov/compound/160134
- Entry on Clofibrat. at: Römpp Online. Georg Thieme Verlag, retrieved 06. Mai 2020.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.