GPR endopeptidase

GPR endopeptidase (EC 3.4.24.78, germination proteinase) is an enzyme.[1] This enzyme catalyses the following chemical reaction:

Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala
Gpr endopeptidase
Identifiers
EC number3.4.24.78
CAS number75718-32-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme participates in spore germination in Bacillus megaterium.

References

  1. Ponnuraj K, Rowland S, Nessi C, Setlow P, Jedrzejas MJ (June 2000). "Crystal structure of a novel germination protease from spores of Bacillus megaterium: structural arrangement and zymogen activation". Journal of Molecular Biology. 300 (1): 1–10. doi:10.1006/jmbi.2000.3849. PMID 10864493.
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