Guanidinodeoxy-scyllo-inositol-4-phosphatase

In enzymology, a guanidinodeoxy-scyllo-inositol-4-phosphatase (EC 3.1.3.40) is an enzyme that catalyzes the chemical reaction

1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O 1-guanidino-1-deoxy-scyllo-inositol + phosphate
guanidinodeoxy-scyllo-inositol-4-phosphatase
Identifiers
EC number3.1.3.40
CAS number9055-28-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate and H2O, whereas its two products are 1-guanidino-1-deoxy-scyllo-inositol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase. Other names in common use include 1-guanidino-scyllo-inositol 4-phosphatase, and 1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase.

References

    • Walker MS, Walker JB (1971). "Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate". J. Biol. Chem. 246 (22): 7034–40. PMID 4331203.


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