Mitobronitol

Mitobronitol (1,6-dibromo-1,6-dideoxy-D-mannitol) is a brominated analog of mannitol. It is an anticancer drug that is classified as an alkylating agent.[2]

Mitobronitol
Names
Preferred IUPAC name
1,6-Dibromo-1,6-dideoxy-D-mannitol
Systematic IUPAC name
1,6-Dibromohexane-2,3,4,5-tetrol[1]
Identifiers
  • 488-41-5 (2S,3S,4S,5S)-2,3,4,5-tetrol Y
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.006.979
EC Number
  • 207-676-8
KEGG
MeSH Mitobronitol
RTECS number
  • OP2800000 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
UNII
Properties
C6H12Br2O4
Molar mass 307.966 g·mol−1
Appearance Colourless crystals
log P −0.226 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Acidity (pKa) 12.609 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Basicity (pKb) 1.388 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Pharmacology
L01AX01 (WHO)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. "Mitolactol - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Identification. Retrieved 22 June 2012.
  2. Mitobronitol, The Centre for Cancer Education
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