Rectum

The blood supply of the rectum changes between the top and bottom portions.[7] The top two thirds is supplied by the superior rectal artery. The lower third is supplied by the middle and inferior rectal arteries.[7]

The superior rectal artery is a single artery that is a continuation of the inferior mesenteric artery, when it crosses the pelvic brim.[7] It enters the mesorectum at the level of S3, and then splits into two branches, which run at the lateral back part of the rectum, and then the sides of the rectum. These then end in branches in the submucosa, which join with (anastamose) with branches of the middle and inferior rectal arteries.[7]

• 
  Arteries of the pelvis
• 
  Blood vessels of the rectum and anus

The microanatomy of the wall of the rectum is similar to the rest of the gastrointestinal tract;[8] namely, that it possesses a mucosa with a lining of a single layer of column-shaped cells with mucous-secreting goblet cells interspersed, resting on a lamina propria, with a layer of smooth muscle called muscularis mucosa. This sits on an underlying submucosa of connective tissue, surrounded by a muscularis propria of two bands of muscle, an inner circular band and an outer longitudinal one.[9] There are a higher concentration of goblet cells in the rectal mucosa than other parts of the gastrointestinal tract.[8]

The lining of the rectum changes sharply at the point where the rectum meets the anus. Here, the lining changes from the column-shaped cells of the rectum to multiple layers of flat cells.[8]

• 
  Cross-section microscopic shot of the rectal wall
• 
  Dog Rectum cross-section (40×)
• 
  Microscopic cross-section of the rectum of a dog (400×), showing a high concentration of goblet cells in amongst the column-shaped lining. Goblet cells can be seen as the circular cells with a clear inner material (cytoplasm).

For the diagnosis of certain ailments, a rectal exam may be done. These include faecal impaction, prostatic cancer and benign prostatic hypertrophy in men, faecal incontinence, and internal haemorrhoids.[11] Forms of medical imaging used to examine the rectum include CT scans and MRI scans. An ultrasound probe may be inserted into the rectum to view nearby structures such as the prostate.

Colonoscopy and sigmoidoscopy are forms of endoscopy that use a guided camera to directly view the rectum. The instruments may have the ability to take biopsies if needed, for diagnosis of diseases such as cancer. A proctoscope is another instrument that is used to visualise the rectum.

Body temperature can also be taken in the rectum. Rectal temperature can be taken by inserting a medical thermometer not more than 25 mm (1 inch) into the rectum via the anus. A mercury thermometer should be inserted for 3 to 5 minutes; a digital thermometer should remain inserted until it beeps. Normal rectal temperature generally ranges from 36 to 38 °C (96.8 to 100.4 °F) and is about 0.5 °C (1 °F) above oral (mouth) temperature and about 1 °C (2 °F) above axilla (armpit) temperature. Availability of less invasive temperature-taking methods including tympanic (ear) and forehead thermometers has facilitated reduced use of this method.

Some medications are also administered via the rectum (Latin: per rectum).[12] By their definitions, suppositories are inserted, and enemas are injected into the rectum.[13][14] Medications might be given via the rectum to relieve constipation, to treat conditions near the rectum, such as fissures or haemorrhoids, or to give medications that are systemically active when taking them by mouth is not possible.[15] People do not tend to like medications administered by this route because of both cultural issues, discomfort, and issues that may affect the medication working, such as leakage.[15]

One cause of constipation is faecal impaction in the rectum, in which a dry, hard stool forms. Constipation is most commonly because of dietary and lifestyle factors such as inadequate hydration, immobility, and lack of dietary fibre, although there are many potential causes.[16] Such causes may include obstruction because of narrowing, local disease (such as Chron's disease, fissues or haemorrhoids), or diseases that affect the neurological control of the bowel, or slow bowel transit time, including spinal cord injury and multiple sclerosis; use of medications such as opioids, and conditions such as diabetes mellitus, as well as severe illness.[16] High calcium levels and low thyroid activity may also cause constipation.[16]

Testing might be carried out to investigate the cause. This may include blood tests such as biochemistry, calcium levels, thyroid function tests. [16] A a digital rectal exam may be performed to see if there is stool in the rectum, and if there is an obstruction.[16] When symptoms such as weight loss, bleeding through the rectum, or pain are present, additional investigations such as a CT scan may be ordered.[16] If constipation persists despite trying simple treatments, testing may also include anal manometry to measure pressures in the anus and rectum, electrophysiological studies, and magnetic resonance proctography.[16]

In general however, constipation is treated by improving factors such as hydration, exercise, and dietary fibre.[16] Laxatives may be used. Constipation that persists may require enemas or suppositories. Sometimes, use of the fingers or hand (manual evacuation) is required. Although peristalsis in the colon delivers material to the rectum, laxatives such as bisacodyl or senna that induce peristalsis in the large bowel do not appear to initiate peristalsis in the rectum. They induce a sensation of rectal fullness and contraction that frequently leads to defecation, but without the distinct waves of activity characteristic of peristalsis.[17]

• Proctitis is inflammation of the anus and the rectum.
• Ulcerative colitis, one form of inflammatory bowel disease that causes ulcers that affect the rectum. This may be episodic, over a person's lifetime. These may cause blood to be visible in the stool. As of 2014 the cause is unknown.

• Rectal cancer, a subgroup of colorectal cancer specific to the rectum.

Other diseases of the rectum include:

• Rectal prolapse, referring to the prolapse of the rectum into the anus or external area. This is commonly caused by a weakened pelvic floor after childbirth
• In the context of mesenteric ischemia, the upper rectum is sometimes referred to as Sudak's point and is of clinical importance as a watershed region between the inferior mesenteric artery circulation and the internal iliac artery circulation via the middle rectal artery and thus prone to ischemia. Sudak's point is often referred to along with Griffith's point at the splenic flexure as a watershed region.

Due to the proximity of the anterior wall of the rectum to the vagina in females or to the prostate in males, and the shared nerves thereof, rectal stimulation or penetration can result in sexual arousal.

English rectum is derived from the full Latin expression intestinum rectum.[18] The English name straight gut[19] truly expresses the literal meaning of this expression, as Latin rectum means straight,[20] and intestinum means gut.[20] This Latin expression is a translation[21][22] of Ancient Greek ἀπευθυσμένον ἔντερον, derived from ἀπευθύνειν, to make straight,[23] and ἔντερον, gut,[23] attested in the writings of Greek physician Galen.[21][22] During his anatomic investigations on animal corpses, Galen observed the rectum to be straight instead of curved as in humans.[21][22] The expressions ἀπευθυσμένον ἔντερον and intestinum rectum are therefore not appropriate descriptions of the rectum in humans. Apeuthysmenon[24] can be considered as Latinization of ἀπευθυσμένον ἔντερον and euthyenteron[25] has a similar meaning (εὐθύς = straight[23]). Much of the knowledge of the anatomy of the rectum comes from detailed descriptions provided byn Andreus Vesalius in 1543.[26]