Retinyl-palmitate esterase
In enzymology, a retinyl-palmitate esterase (EC 3.1.1.21) is an enzyme that catalyzes the chemical reaction
- retinyl palmitate + H2O retinol + palmitate
| retinyl-palmitate esterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.1.21 | ||||||||
| CAS number | 9063-69-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are retinyl palmitate and H2O, whereas its two products are retinol and palmitate.
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is retinyl-palmitate palmitohydrolase. Other names in common use include retinyl palmitate hydrolase, retinyl palmitate hydrolyase, and retinyl ester hydrolase. This enzyme participates in retinol metabolism.
References
- Mahadevan S, Ayyoub NI, Roels OA (1966). "Hydrolysis of retinol palmitate by rat liver". J. Biol. Chem. 241 (1): 57–64. PMID 5901057.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.