Ribonuclease U2
Ribonuclease U2 (EC 3.1.27.4, purine specific endoribonuclease, ribonuclease U3, RNase U3, RNase U2, purine-specific ribonuclease, purine-specific RNase, Pleospora RNase, Trichoderma koningi RNase III, ribonuclease (purine)) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates
| Ribonuclease U2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.27.4 | ||||||||
| CAS number | 37205-57-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
References
- Glitz DG, Dekker CA (October 1964). "Studies on a ribonuclease from Ustilago sphaerogena. I. Purification and properties of the enzyme". Biochemistry. 3 (10): 1391–9. doi:10.1021/bi00898a001. PMID 14230791.
- Glitz DG, Dekker CA (October 1964). "Studies on a ribonuclease from Ustilago sphaerogena. II. Specificity of the enzyme". Biochemistry. 3 (10): 1399–406. doi:10.1021/bi00898a002. PMID 14230792.
- Uchida T, Egami F (1971). "Microbial ribonucleases with special reference to RNases T1, T 2, N 1, and U2". In Boyer PD (ed.). The Enzymes. 4 (3rd ed.). New York: Academic Press. pp. 205–250.
External links
- Ribonuclease+U2 at the US National Library of Medicine Medical Subject Headings (MeSH)
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