A-1,4-glucan-protein synthase (UDP-forming)
Alpha-1,4-glucan-protein synthase (UDP-forming) (EC 2.4.1.112, UDP-glucose:protein glucosyltransferase, glycogen initiator synthase, UDPGlc:protein transglucosylase, UPTG, uridine diphosphoglucose protein transglucosylase I, proglycogen synthase, uridine diphosphoglucose-protein 4-alpha-glucosyltransferase, uridine diphosphoglucose-protein glucosyltransferase, UDP-glucose protein transglucosylase, UDP-glucose-protein glucosyltransferase, uridine diphosphate glucose-protein transglucosylase I) is an enzyme with systematic name UDP-glucose:protein 4-alpha-glucosyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- UDP-glucose + protein UDP + alpha-D-glucosyl-protein
| Alpha-1,4-glucan-protein synthase (UDP-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.112 | ||||||||
| CAS number | 152478-54-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme builds up alpha-1,4-glucan chains covalently bound to protein.
References
- Barengo R, Krisman CR (May 1978). "Initiation of glycogen biosynthesis in Escherichia coli. Studies of the properties of the enzymes involved". Biochimica et Biophysica Acta (BBA) - General Subjects. 540 (2): 190–6. doi:10.1016/0304-4165(78)90131-9. PMID 418819.
- Butler NA, Lee EY, Whelan WJ (May 1977). "A protein-bound glycogen component of rat liver". Carbohydrate Research. 55: 73–82. doi:10.1016/s0008-6215(00)84444-4. PMID 861979.
- Krisman CR, Barengo R (March 1975). "A precursor of glycogen biosynthesis: alpha-1,4-glucan-protein". European Journal of Biochemistry. 52 (1): 117–23. doi:10.1111/j.1432-1033.1975.tb03979.x. PMID 809265.
External links
- Alpha-1,4-glucan-protein+synthase+(UDP-forming) at the US National Library of Medicine Medical Subject Headings (MeSH)
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