Heteroglycan alpha-mannosyltransferase
In enzymology, a heteroglycan alpha-mannosyltransferase (EC 2.4.1.48) is an enzyme that catalyzes the chemical reaction
- GDP-mannose + heteroglycan GDP + 2(or 3)-alpha-D-mannosyl-heteroglycan
| heteroglycan alpha-mannosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.48 | ||||||||
| CAS number | 37277-57-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are GDP-mannose and heteroglycan, whereas its 3 products are GDP, 2-alpha-D-mannosyl-heteroglycan, and 3-alpha-D-mannosyl-heteroglycan.
This enzyme belongs to the family of glycosyltransferases, to be specific the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase. Other names in common use include GDP mannose alpha-mannosyltransferase, and guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase.
References
- Garancis JC, Ankel H, Ankel E, Schutzbach JS (1970). "Mannosyl transfer in Cryptococcus laurentii". J. Biol. Chem. 245 (15): 3945–55. PMID 5492958.
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