Lactotriaosylceramide beta-1,4-galactosyltransferase
Lactotriaosylceramide beta-1,4-galactosyltransferase (EC 2.4.1.275, beta4Gal-T4, UDP-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide beta-1,4-galactosyltransferase) is an enzyme with systematic name UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase.[1] This enzyme catalyses the following chemical reaction
- UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
| Lactotriaosylceramide beta-1,4-galactosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.275 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
References
- Schwientek T, Almeida R, Levery SB, Holmes EH, Bennett E, Clausen H (November 1998). "Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis". The Journal of Biological Chemistry. 273 (45): 29331–40. doi:10.1074/jbc.273.45.29331. PMID 9792633.
External links
- Lactotriaosylceramide+beta-1,4-galactosyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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