U.S. Route 220 in Pennsylvania

View north along US 220 entering Pennsylvania from Maryland

US 220 enters Pennsylvania from Maryland in Cumberland Valley Township, Bedford County to the north of Cumberland, Maryland. From the state line, the route heads northeast as a two-lane undivided road as it passes through a narrow agricultural valley surrounded by forested mountains. As the highway approaches Bedford, US 220 Business (US 220 Bus.) splits off to head into Bedford while US 220 bypasses the borough to the west. The bypass is initially two lanes, but widens into a four-lane freeway before it reaches an interchange with US 30 Bus. A short distance later, the route comes to a cloverleaf interchange with US 30, which bypasses downtown Bedford to the north as a freeway. The US 220 freeway continues north away from Bedford to a trumpet interchange that serves US 220 Bus. and also provides indirect access to I-70/I-76 (Pennsylvania Turnpike). It is at this interchange that I-99 begins and becomes concurrent with US 220.[1][2]

I-99/US 220 north near Bald Eagle, Pennsylvania in October 2011

I-99/US 220 continues north through farmland and continues to the next interchange near Cessna, which serves Pennsylvania Route 56 (PA 56) and the northern terminus of US 220 Bus. Farther north, the freeway comes to the PA 869 exit in Saint Clairsville. The highway continues through a mix of farms and forests, with a diamond interchange at Sarah Furnace Road that provides access to Blue Knob State Park. I-99/US 220 crosses into Blair County and comes to an interchange with the southern terminus of US 220 Bus. that serves the Altoona area. The freeway passes Claysburg and East Freedom before it reaches a trumpet interchange that provides access to PA 36 and PA 164 to the east. The highway bypasses Newry to the east prior to heading into more developed surroundings as it enters the Hollidaysburg area. Here, I-99/US 220 has an interchange that serves US 22 and PA 764. Past this interchange, the freeway curves east and heads into Altoona, where it comes to an interchange with US 220 Bus. in a commercial area near the Logan Valley Mall. The highway curves north again and comes to the Frankstown Road exit which provides access to PA 36 and Peoples Natural Gas Field, home of the Altoona Curve baseball team. I-99/US 220 continues along the eastern edge of Altoona and comes to the 17th Street exit which serves downtown Altoona. The road continues between development to the west and forested mountains to the east as it heads away from Altoona and reaches an interchange with the northern terminus of PA 764.[1][2]

I-99/US 220 continues northeast between a mountain to the east in an agricultural valley to the west, coming to an interchange with the southern terminus of PA 865 near Bellwood. Near Tipton, the freeway has a trumpet interchange with US 220 Bus. that provides access to DelGrosso's Amusement Park. The highway continues to Tyrone, where it crosses the Little Juniata River before an interchange with PA 453. Past Tyrone, I-99/US 220 passes through forested areas and reaches a diamond interchange that serves PA 350 and the northern terminus of US 220 Bus. near Bald Eagle. From here, the freeway continues into Centre County and runs through rural areas before turning north to bypass Port Matilda to the west. I-99/US 220 has an interchange with the southern terminus of US 220 Alternate (US 220 Alt.) before the two routes merge into the US 322 freeway and head east concurrent with US 322. The freeway heads northeast away from Port Matilda and continues through more forests. I-99/US 220/US 322 curves southeast and reaches an interchange with Gray's Woods Boulevard near Gray's Woods. A short distance later, US 322 Bus. splits off at a northbound exit and southbound entrance to head into State College. Immediately after this interchange, a southbound exit and northbound entrance serves Valley Vista Drive and provides access to US 322 Bus. from southbound I-99/US 220/westbound US 322. The freeway continues east into more developed areas with some woods and comes to a diamond interchange at Waddle Road that serves Toftrees. The highway passes to the north of the Pennsylvania State University campus before I-99/US 220 split from the US 322 freeway at an interchange that also has access to the university by way of East Park Avenue.[1][2]

Past US 322, I-99/US 220 continues northeast away from State College through a mix of farmland and woodland. An interchange serves Shiloh Road before the highway comes to the PA 150 exit near State Correctional Institution – Rockview. The freeway has a northbound exit and southbound entrance at Harrison Road before it merges with PA 26. From here, I-99 and US 220 continue north concurrent with PA 26 as the highway heads through farmland to the east of Bellefonte. An interchange at PA 550 provides access to Bellefonte. The highway curves to the northeast and the freeway and I-99 end before the highway reaches an interchange with I-80. At this interchange, PA 26 continues to the northeast as a two-lane road. US 220 Alt. rejoins from the west along I-80, and US 220 heads east concurrent with I-80 on a four-lane freeway.[1][2]

US 220 near I-80 exit 178 in Clinton County

I-80 and US 220 head northeast through a mix of woodland and farms, crossing into Clinton County. Here, the highway comes to a diamond interchange with PA 64. US 220 continues east along I-80 before it splits from the interstate at another diamond interchange. From here, US 220 heads northwest as a two-lane undivided surface road through farmland with some development. The route transitions into a four-lane freeway as it comes to an interchange with PA 64 and PA 477 to the south of Mill Hall. The freeway passes through forested mountains before bypassing Mill Hall to the east. US 220 curves east and has a trumpet interchange that serves PA 150. The highway turns northeast and crosses Bald Eagle Creek prior to a diamond interchange with the eastern terminus of PA 120 to the south of Lock Haven. US 220 continues east and crosses Bald Eagle Creek again before leaving the Lock Haven area and heading into rural surroundings. The route has an interchange with McElhattan Drive that serves McElhattan. The freeway passes through farmland and crosses the West Branch Susquehanna River before it comes to an interchange with the northern terminus of PA 150 near Avis. The US 220 freeway bypasses Avis to the southeast and continues to the PA 44 exit, at which point that route joins US 220.[1][2]

The freeway crosses Pine Creek into Lycoming County and heads to the north of Jersey Shore. An interchange at Thomas Street provides access to the borough. At the east end of Jersey Shore, PA 44 splits from the US 220 freeway to head south. US 220 continues east to the north of the West Branch Susquehanna River into rural areas. The freeway ends prior to an at-grade intersection with the southern terminus of PA 287, at which point US 220 continues east as a four-lane divided surface road. The median widens as the highway passes through Larrys Creek. The route continues east through farmland with some development, curving northeast before heading back to the east. US 220 becomes a freeway again as it approaches Williamsport, with the first exit being a northbound exit and southbound entrance at 4th Street. The highway heads into Williamsport and heads into industrial areas to the north of the river, with an interchange at Reach Road serving the Reach Road Industrial Park. The freeway passes over Lycoming Creek immediately before an interchange with the US 15 freeway.[1][2]

Looking west on I-180/US 15/US 220 from the Carl E. Stotz Memorial Little League Bridge in Williamsport

At this point, I-180 begins and US 220 continues east concurrent with I-180 and US 15. The highway continues alongside the West Branch Susquehanna River and has an interchange at Maynard Street that serves the Pennsylvania College of Technology and a northbound exit and southbound entrance at Hepburn Street. In downtown Williamsport, US 15 splits from I-180 and US 220 by heading southeast across the river into South Williamsport. I-180/US 220 continues northeast through more developed areas, with a southbound exit and northbound entrance at Basin Street. The freeway leaves the city limits and has an interchange with Northway Road in Faxon. The highway has an interchange with 3rd Street prior to crossing the Loyalsock Creek and heading to the north of Montoursville. In this area, I-180/US 220 comes to an interchange with the southern terminus of PA 87. On the eastern edge of Montoursville, an interchange is located at Fairfield Road. The freeway heads into a mix of farmland and woodland, reaching an interchange that serves the Lycoming Mall. At the next interchange, US 220 splits from I-180.[1][2]

US 220 in Shrewsbury Township in Lycoming County

Upon splitting from I-180, US 220 heads east as a two-lane undivided surface road through agricultural areas. The route reaches Hughesville, where it intersects the northern terminus of PA 405. At this point, US 220 turns north and continues to Picture Rocks. Here, the route has a junction with the eastern terminus of PA 864. Past Picture Rocks, the road winds northeast along the banks of Muncy Creek through forested areas. US 220 enters Sullivan County and intersects PA 42 in Beech Glen. The two routes run north together until Muncy Valley, where PA 42 splits to the northwest. US 220 continues northeast concurrent with PA 42 Truck through more forests to Laporte, where it has an intersection with the northern terminus of PA 42 and PA 42 Truck. A short distance north of Laporte, the route encounters the southern terminus of PA 154. The road passes through more rural areas before PA 87 joins in from the west prior to reaching Dushore. In Dushore, PA 87 splits to the east. US 220 heads north through a mix of fields and forests as it continues into Bradford County. The route passes through New Albany before continuing north through more forests. In Monroe, the road has an intersection with the eastern terminus of PA 414.[1][2]

US 220 heads northeast through more rural areas before bypassing Towanda to the west. The two-lane undivided bypass has an interchange at Patterson Boulevard that provides access to the borough. The route curves west then northwest as it comes to a diamond interchange with US 6. Past this, US 220 continues north as a two-lane undivided road through a mix of farmland and woodland along the west bank of the Susquehanna River, passing through Ulster and Milan. South of Athens, the route intersects the southern terminus of PA 199 before turning into a four-lane freeway that bypasses the Penn-York Valley boroughs of Athens, Sayre, and South Waverly to the west. US 220 crosses the Chemung River and comes to a diamond interchange at West Pine Street that serves Athens. The highway continues between the river to the west and developed areas to the east before it reaches an interchange at Mile Lane Road that serves Sayre and South Waverly. The route enters South Waverly and comes to its northern terminus at an interchange with I-86/NY 17, which is maintained by the state of New York despite being in Pennsylvania. Past the northern terminus, the road crosses the New York border and ends a short distance later at Chemung Street in Waverly.[1][2]

US 220 northbound in Towanda