List of Missouri ballot measures
The following is a list of statewide initiatives and referenda modifying state law and proposing state constitutional amendments in Missouri, sorted by election.
| Elections in Missouri |
|---|
 |
2000s
2004
| Proposal | Passed | YES votes | YES % | NO votes | NO % | Description |
|---|---|---|---|---|---|---|
| Amendment 2 |  Yes |
1,055,771 | 70.61% | 439,529 | 29.39% | prohibited same-sex marriages from being recognized in Missouri. |
2006
| Proposal | Passed | YES votes | YES % | NO votes | NO % | Description |
|---|---|---|---|---|---|---|
| Amendment 2 | Yes |
1,085,396 | 51.2% | 1,034,596 | 48.8% | Missouri Stem Cell Research and Cures Initiative. Allows any stem cell research and therapy in the U.S. state of Missouri that is legal under federal law, including somatic cell nuclear transfer to produce human embryos for stem cell production. It prohibits cloning or attempting to clone a human being. |
2010s
2018
| Proposal | Passed | YES votes | YES % | NO votes | NO % | Description |
|---|---|---|---|---|---|---|
| Proposal A |  No |
453,283 | 32.53% | 939,973 | 67.47% | Senate Bill 19, which would enact a right-to-work law |
| Proposal | Passed | YES votes | YES % | NO votes | NO % | Description |
|---|---|---|---|---|---|---|
| Amendment 1 | Yes |
1,469,093 | 62.02% | 899,613 | 37.98% | Lobbying, Campaign Finance, and Redistricting Initiative. |
| Amendment 2 | Yes |
1,583,227 | 65.59% | 830,631 | 34.41% | Medical Marijuana and Veteran Healthcare Services Initiative. Would legalize marijuana for medical purposes, tax sales at 4 percent, and redistribute revenue to healthcare services, job training, housing assistance, and other services for veterans |
| Amendment 3 | No |
754,007 | 31.50% | 1,639,622 | 68.50% | Medical Marijuana and Biomedical Research and Drug Development Institute Initiative. Would legalize marijuana for medical purposes, tax sales at 15 percent, and redistribute revenue to the creation of a Biomedical Research and Drug Development Institute |
2020s
2020
| Proposal | Passed | YES votes | YES % | NO votes | NO % | Description |
|---|---|---|---|---|---|---|
| Amendment 2 | Yes |
672,967 | 53.25% | 590,809 | 46.75% | Amends state constitution to expand Medicaid under the Patient Protection and Affordable Care Act |
| Proposal | Passed | YES votes | YES % | NO votes | NO % | Description |
|---|---|---|---|---|---|---|
| Amendment 1 | TBD | TBD | TBD | TBD | TBD | Sets a two-term limit for state executive officials. |
| Amendment 3 | TBD | TBD | TBD | TBD | TBD | Repeal many of the redistricting provisions of 2018's Amendment 3. |
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