Myelocyte

Myelocyte
Details
Precursor	Promyelocyte
Gives rise to	Metamyelocyte
Location	Bone marrow
Identifiers
TH	H2.00.04.3.04004
	Anatomical terms of microanatomy;

A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).

Basophilic[1]

Eosinophilic[2]

Neutrophilic[3]

Structure

When stained with the usual dyes, the cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though myelocytes are smaller cells.

Numerous cytoplasmic granules are present in the more mature forms of myelocytes. Neutrophilic and eosinophilic granules are peroxidase-positive, while basophilic granules are not.

The nuclear chromatin is coarser than that observed in a promyelocyte, but it is relatively faintly stained and lacks a well-defined membrane.

The nucleus is fairly regular in contour (not indented), and seems to be 'buried' beneath the numerous cytoplasmic granules. (If the nucleus were indented, it would likely be a metamyelocyte.)

Measurement

There is an internationally agreed method of counting blasts, with results from M1 upwards.

Development

Promyelocyte --> Myelocytes --> metamyelocytes.

Additional images

Hematopoiesis

References

Histology image:01809loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.
Histology image:01810loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.
Histology image:01804loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.

External links

Neutrophilic Myelocyte Presented by the University of Virginia
Eosinophilic Myelocyte Presented by the University of Virginia
Basophilic Myelocyte Presented by the University of Virginia
Image at queensu.ca

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[1] Histology image:01809loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.

[2] Histology image:01810loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.

[3] Histology image:01804loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.