N-Terminal peptide of proopiomelanocortin

The N-terminal peptide/fragment of proopiomelanocortin (NPP; N-POMC), also known as pro-γ-MSH, is a naturally occurring, endogenous metabolite of the polypeptide proopiomelanocortin (POMC).

N-Terminal peptide of proopiomelanocortin
Identifiers
SymbolN-POMC
Alt. symbolsNPP; pro-γ-MSH

N-POMC is also a precursor for γ1-MSH, γ2-MSH, and γ3-MSH, and can form them through proteolytic cleavage.

N-POMC is an adrenal growth factor.[1]

See also

References

  1. Bicknell AB (May 2016). "60 YEARS OF POMC: N-terminal POMC peptides and adrenal growth". Journal of Molecular Endocrinology. 56 (4): T39-48. doi:10.1530/JME-15-0269. PMID 26759392.
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