Fromanvirus

Fromanvirus (synonyms L5-like viruses, L5-like phages, L5likevirus) is a genus of viruses in the order Caudovirales, in the family Siphoviridae. Bacteria serve as natural hosts, with transmission achieved through passive diffusion. There are currently 59 species in this genus, including the type species Mycobacterium virus L5.[1][2][3]

Fromanvirus
Virus classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Uroviricota
Class: Caudoviricetes
Order: Caudovirales
Family: Siphoviridae
Genus: Fromanvirus
Type species
Mycobacterium virus L5

Taxonomy

Group: dsDNA

[2]

Structure

Fromanviruses are nonenveloped, with a head and tail. The icosahedral head is about 60 nm in diameter, with covalently linked capsid proteins. The tail is long and flexible, at about 135 nm long, 8 nm wide, and has a terminal knob with one short tail fiber.[1]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
FromanvirusHead-TailT=7Non-envelopedLinearMonopartite

Genome

Bxb1, D29, and L5 and have been fully sequenced. They range between 49k and 53k nucleotides, with 79 to 90 proteins. Their complete genomes are available here[3]

Life cycle

The virus attaches to the host cell's adhesion receptors using its terminal fiber, and ejects the viral DNA into the host cytoplasm via long flexible tail ejection system. Viral replication is cytoplasmic. Replication follows the replicative transposition model. DNA-templated transcription is the method of transcription. Once the viral genes have been replicated, the procapsid is assembled and packed. The tail is then assembled and the mature virions are released via lysis. Bacteria serve as the natural host. Transmission routes are passive diffusion.[1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
FromanvirusBacteriaNoneInjectionLysisCytoplasmCytoplasmPassive diffusion

History

According to ICTV's 1996 report, the genus L5likevirus was first accepted under the name L5-like phages, assigned only to family Siphoviridae. The whole family was moved to the newly created order Caudovirales in 1998, and the genus was renamed to L5-like viruses in ICTV's seventh report in 1999. In 2012, the genus was renamed again, this time to L5likevirus.[2] The genus was later renamed to Fromanvirus.

References
  1. "Viral Zone". ExPASy. Retrieved 1 July 2015.
  2. "Virus Taxonomy: 2019 Release". talk.ictvonline.org. International Committee on Taxonomy of Viruses. Retrieved 5 May 2020.
  3. NCBI. "L5likevirus Complete Genomes". Retrieved 18 February 2015.

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