Globuloviridae
Globuloviridae is a family of hyperthermophilic archaeal viruses. Crenarchaea of the genera Pyrobaculum and Thermoproteus serve as natural hosts. There are currently only two species in this family, Pyrobaculum spherical virus and Thermoproteus tenax spherical virus 1, included into a single genus, Globulovirus.[1][2] Two tentative members of the family, Pyrobaculum spherical virus 2 [3] and Thermoproteus spherical piliferous virus 1 [4] have been isolated but not officially classified.
| Globuloviridae | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | incertae sedis |
| Kingdom: | incertae sedis |
| Phylum: | incertae sedis |
| Class: | incertae sedis |
| Order: | incertae sedis |
| Family: | Globuloviridae |
| Genera | |
| |
Taxonomy
Group: dsDNA
- Family: Globuloviridae
- Genus: Globulovirus
- Pyrobaculum spherical virus
- Thermoproteus tenax spherical virus 1
Structure
Virions in the Globuloviridae are spherical and enveloped. The diameter is around 100 nm. Genomes are linear dsDNA and non-segmented, around 20-30kb in length.[1][2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Globulovirus | Spherical | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is cytoplasmic. DNA-templated transcription is the method of transcription. Pyrobaculum and Thermoproteus archaea serve as the natural host. Transmission routes are passive diffusion.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Globulovirus | Pyrobaculum and Thermoproteus archaea | None | Injection | Budding | Cytoplasm | Cytoplasm | Passive diffusion |
References
- Prangishvili, D; Krupovic, M; ICTV Report Consortium (2018). "ICTV Virus Taxonomy Profile: Globuloviridae". The Journal of General Virology. 99 (10): 1357–1358. doi:10.1099/jgv.0.001123. PMID 30091697.
- "Viral Zone". ExPASy. Retrieved 15 June 2015.
- Baquero, DP; Contursi, P; Piochi, M; Bartolucci, S; Liu, Y; Cvirkaite-Krupovic, V; Prangishvili, D; Krupovic, M (2020). "New virus isolates from Italian hydrothermal environments underscore the biogeographic pattern in archaeal virus communities". The ISME Journal. doi:10.1038/s41396-020-0653-z. PMID 32322010.
- Hartman, R; Biewenga, L; Munson-McGee, J; Refai, M; Boyd, ES; Bothner, B; Lawrence, CM; Young, M (2020). "Discovery and Characterization of TSPV1: A Spherical Archaeal Virus Decorated with Unusual Filaments". Journal of Virology. 94 (11). doi:10.1128/JVI.00036-20. PMID 32213609.
- Häring M, Peng X, Brügger K, Rachel R, Stetter KO, Garrett RA, Prangishvili D (2004). "Morphology and genome organization of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: a novel virus family, the Globuloviridae". Virology. 323 (2): 233–242. doi:10.1016/j.virol.2004.03.002. PMID 15193919.