Gammapapillomavirus
Gammapapillomavirus is a genus of viruses, in the family Papillomaviridae.[1] Human serve as natural hosts. There are currently 27 species in this genus including the type species Gammapapillomavirus 1. Diseases associated with this genus include: warts, papilloma.[2][3]
| Gammapapillomavirus | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Zurhausenvirales |
| Family: | Papillomaviridae |
| Genus: | Gammapapillomavirus |
| Type species | |
| Gammapapillomavirus 1 | |
Taxonomy
Group: dsDNA
- Family: Papillomaviridae
- Genus: Gammapapillomavirus
- Gammapapillomavirus 1
- Gammapapillomavirus 2
- Gammapapillomavirus 3
- Gammapapillomavirus 4
- Gammapapillomavirus 5
- Gammapapillomavirus 6
- Gammapapillomavirus 7
- Gammapapillomavirus 8
- Gammapapillomavirus 9
- Gammapapillomavirus 10
- Gammapapillomavirus 11
- Gammapapillomavirus 12
- Gammapapillomavirus 13
- Gammapapillomavirus 14
- Gammapapillomavirus 15
- Gammapapillomavirus 16
- Gammapapillomavirus 17
- Gammapapillomavirus 18
- Gammapapillomavirus 19
- Gammapapillomavirus 20
- Gammapapillomavirus 21
- Gammapapillomavirus 22
- Gammapapillomavirus 23
- Gammapapillomavirus 24
- Gammapapillomavirus 25
- Gammapapillomavirus 26
- Gammapapillomavirus 27
Structure
Viruses in Gammapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Gammapapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Human serve as the natural host. Transmission routes are contact.[2]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Gammapapillomavirus | Humans | Epithelial: mucous; epithelial: skin | Cell receptor endocytosis | Lysis | Nucleus | Nucleus | Contact |
References
- Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
- "Viral Zone". ExPASy. Retrieved 15 June 2015.
- "ICTV Report Papillomaviridae".