OR2A5

Olfactory receptor 2A5 is a protein that in humans is encoded by the OR2A5 gene.[4][5]

OR2A5
Identifiers
AliasesOR2A5, OR2A11P, OR2A26, OR2A8, OR7-138, OR7-141, olfactory receptor family 2 subfamily A member 5
External IDsMGI: 3030282 HomoloGene: 64846 GeneCards: OR2A5
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q35Start144,048,948 bp[1]
End144,058,845 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

393046

258270

Ensembl

ENSG00000221836
ENSG00000284896

ENSMUSG00000043119

UniProt

Q96R48

Q8VES9

RefSeq (mRNA)

NM_012365

NM_146273

RefSeq (protein)

NP_036497

NP_666385

Location (UCSC)Chr 7: 144.05 – 144.06 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ENSG00000284896 GRCh38: Ensembl release 89: ENSG00000221836, ENSG00000284896 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
  5. "Entrez Gene: OR2A5 olfactory receptor, family 2, subfamily A, member 5".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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