OR3A3

Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.[4][5][6]

OR3A3
Identifiers
AliasesOR3A3, OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P, olfactory receptor family 3 subfamily A member 3
External IDsMGI: 3030245 HomoloGene: 74999 GeneCards: OR3A3
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17p13.2Start3,411,370 bp[1]
End3,424,070 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8392

258704

Ensembl

ENSG00000159961

ENSMUSG00000054406

UniProt

P47888

n/a

RefSeq (mRNA)

NM_012373

NM_146709

RefSeq (protein)

NP_036505

n/a

Location (UCSC)Chr 17: 3.41 – 3.42 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References
  1. GRCh38: Ensembl release 89: ENSG00000159961 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088.
  5. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
  6. "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.