OR2J3

Olfactory receptor 2J3 is a protein that in humans is encoded by the OR2J3 gene.[3]

OR2J3
Identifiers
AliasesOR2J3, 6M1-3, C3HEXS, HS6M1-3, OR6-16, OR6-6, OR6.3.6, ORL671, olfactory receptor family 2 subfamily J member 3
External IDsOMIM: 615016 HomoloGene: 128270 GeneCards: OR2J3
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6p22.1Start29,108,059 bp[1]
End29,114,770 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

442186

n/a

Ensembl

n/a

UniProt

O76001

n/a

RefSeq (mRNA)

NM_001005216

n/a

RefSeq (protein)

NP_001005216

n/a

Location (UCSC)Chr 6: 29.11 – 29.11 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

Genetic variation

A pair of two single-nucleotide polymorphisms, both in the OR2J3 gene, strongly reduce sensitivity to the odorant cis-3-hexen-1-ol, which has a "cut grass" smell.[4]

Ligands

See also

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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