OR5AN1

Olfactory receptor 5AN1 is a protein that in humans is encoded by the OR5AN1 gene.[4]

OR5AN1
Identifiers
AliasesOR5AN1, OR11-244, olfactory receptor family 5 subfamily AN member 1
External IDsOMIM: 615702 MGI: 3031268 HomoloGene: 45029 GeneCards: OR5AN1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q12.1Start59,358,895 bp[1]
End59,371,714 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

390195

258680

Ensembl

ENSG00000176495

ENSMUSG00000095640

UniProt

Q8NGI8

n/a

RefSeq (mRNA)

NM_001004729

NM_146685

RefSeq (protein)

NP_001004729

n/a

Location (UCSC)Chr 11: 59.36 – 59.37 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

Ligands

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000176495 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Entrez Gene: OR5AN1 olfactory receptor, family 5, subfamily AN, member 1".
  5. Ahmed, L.; et al. (2018). "Molecular Mechanism of Activation of Human Musk Receptors OR5AN1 and OR1A1 by (R)-Muscone and Diverse Other Musk-smelling Compounds". Proc. Natl. Acad. Sci. USA. 115 (17): E3950–E3958. doi:10.1073/pnas.1713026115. PMC 5924878. PMID 29632183.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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