T-1123
T-1123 is a carbamate-based acetylcholinesterase inhibitor. It was investigated as a chemical warfare agent starting in 1940. It does not go through the blood-brain barrier due to the charge on quaternary nitrogen. The antidote is atropine.[1] T-1123 is a quaternary ammonium ion. A phenyl carbamate ester is bonded in the meta position to the nitrogen on a diethylmethyl amine.
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| Names | |
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| IUPAC name
N,N-diethyl-N-methyl-3-[(methylcarbamoyl)oxy]anilinium chloride | |
| Other names
AR-16, TL-1217, TL-1299 | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |
| C13H21ClN2O2 | |
| Molar mass | 272.77 g·mol−1 |
| Related compounds | |
Related compounds |
Neostigmine Miotine |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
See also
References
- Gupta, Ramesh C. (2015). Handbook of Toxicology of Chemical Warfare Agents. Academic Press. pp. 338–339. ISBN 9780128004944.
Extra reading
- Robinson, J. P. (1971). The Problem of Chemical and Biological Warfare: The rise of CB weapons. Almqvist & Wiksell.
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