Tetrasodium EDTA

Tetrasodium EDTA
Identifiers
CAS Number	64-02-8 (anhydrous) ; 13235-36-4 (tetrahydrate) ;
3D model (JSmol)	Interactive image;
ChemSpider	5914;
ECHA InfoCard	100.000.522
EC Number	200-573-9;
PubChem CID	6144;
UNII	MP1J8420LU (anhydrous) ; L13NHD21X6 (tetrahydrate) ;
CompTox Dashboard (EPA)	DTXSID3026350 ;
	InChI InChI=1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4 Key: GXFFSKMBMYHTAE-UHFFFAOYSA-J;
	SMILES C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].O.[Na+].[Na+].[Na+].[Na+];
Properties
Chemical formula	C10H12N2Na4O8
Molar mass	380.171 g·mol−1
Appearance	White solid
Hazards
GHS pictograms
GHS Signal word	Danger
GHS hazard statements	H302, H318
GHS precautionary statements	P264, P270, P280, P301+312, P305+351+338, P310, P330, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Tetrasodium EDTA is the salt resulting from the neutralization of ethylenediaminetetraacetic acid with four equivalents of sodium hydroxide (or an equivalent sodium base). It is a white solid that is highly soluble in water. Commercial samples are often hydrated, e.g. Na₄EDTA^.4H₂O. The properties of solutions produced from the anhydrous and hydrated forms are the same, provided they are at the same pH.

It is used as a source of the chelating agent EDTA^4-. A 1% aqueous solution has a pH of approximately 11.3. When dissolved in neutral water, it converts partially to H₂EDTA^2-. Ethylenediaminetetraacetic acid is produced commercially via the intermediacy of tetrasodium EDTA.[1]

Ethylenediaminetetraacetic acid is the acidic form of tetrasodium EDTA.

References

Hart, J. Roger. "Ethylenediaminetetraacetic Acid and Related Chelating Agents". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a10_095.

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[Ullmann-1] Hart, J. Roger. "Ethylenediaminetetraacetic Acid and Related Chelating Agents". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a10_095.

Chelating agents / chelation therapy (V03AC, others)
Copper	Penicillamine^#
Iron	Deferasirox Deferiprone Deferoxamine^#
Lead	BAL^# EDTA^# Dexrazoxane
Thallium	Prussian blue^#
Other	ALA BAPTA DMPS DMSA^# DTPA EGTA
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Consumer food safety
Adulterants, food contaminants	3-MCPD Aldicarb Antibiotic use in livestock Cyanide Formaldehyde HGH controversies Lead poisoning Melamine Mercury in fish Sudan I
Flavorings	Monosodium glutamate (MSG) Salt Sugar High-fructose corn syrup
Intestinal parasites and parasitic disease	Amoebiasis Anisakiasis Cryptosporidiosis Cyclosporiasis Diphyllobothriasis Enterobiasis Fasciolopsiasis Fasciolosis Giardiasis Gnathostomiasis Paragonimiasis Toxoplasmosis Trichinosis Trichuriasis
Microorganisms	Botulism Campylobacter jejuni Clostridium perfringens Cronobacter Enterovirus Escherichia coli O104:H4 Escherichia coli O157:H7 Hepatitis A Hepatitis E Listeria Norovirus Rotavirus Salmonella Vibrio cholerae
Pesticides	Chlorpyrifos DDT Lindane Malathion Methamidophos
Preservatives	Benzoic acid Ethylenediaminetetraacetic acid (EDTA) Sodium benzoate
Sugar substitutes	Acesulfame potassium Aspartame Saccharin Sodium cyclamate Sorbitol Sucralose
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Regulation, standards, watchdogs	Acceptable daily intake E number Food labeling regulations Food libel laws International Food Safety Network ISO 22000 Nutrition facts label Organic certification The Non-GMO Project Quality Assurance International Food Standards Agency
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