Giardiavirus

Giardiavirus is a genus of viruses, in the family Totiviridae. Protozoa serve as natural hosts. There is currently only one species in this genus: the type species Giardia lamblia virus.[1][2]

Giardia lamblia virus
Cryo-EM reconstruction of Giardia lamblia virus (GLV) particle
color based on distance from center
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Duplornaviricota
Class: Chrymotiviricetes
Order: Ghabrivirales
Family: Totiviridae
Genus: Giardiavirus
Species:
Giardia lamblia virus

Structure

Viruses in Giardiavirus are non-enveloped, with icosahedral geometries, and T=2 symmetry. The diameter is around 36 nm. Genomes are linear, around 6277kb in length. The genome has 2 open reading frames.[1]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
GiardiavirusIcosahedralT=2Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded rna virus transcription is the method of transcription. Translation takes place by -1 ribosomal frameshifting, and viral initiation. Protozoa serve as the natural host.[1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
GiardiavirusProtozoaNoneCell receptor endocytosisExocytosisCytoplasmCytoplasmPassive diffusion

Taxonomy

The genus Giardiavirus has on species:[2]

  • Giardia lamblia virus

References
  1. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
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