11β-Hydroxytestosterone

11β-Hydroxytestosterone is an endogenous steroid, a metabolite of testosterone.[1][2][3]

11β-Hydroxytestosterone
Names
IUPAC name
11β,17β-dihydroxyandrost-4-ene-3-one
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.162.057
EC Number
  • 634-040-0
KEGG
Properties
C19H28O3
Molar mass 304.430 g·mol−1
Hazards
GHS pictograms
GHS Signal word Danger
H351, H360
P201, P202, P281, P308+313, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References

  1. Storbeck KH, Mostaghel EA (2019). "Canonical and Noncanonical Androgen Metabolism and Activity". Advances in Experimental Medicine and Biology. 1210: 239–277. doi:10.1007/978-3-030-32656-2_11. ISBN 978-3-030-32655-5. PMID 31900912. CYP11B1 and 2 have also been shown to 11β-hydroxylate T, yielding 11β-hydroxytestosterone (11OHT), though the levels produced by the adrenal are low due to the limited availability of adrenal derived T
  2. Stárka L, Dušková M, Vítků J (September 2020). "11-Keto-testosterone and other androgens of adrenal origin". Physiological Research. 69 (Suppl 2): S187–S192. doi:10.33549/physiolres.934516. PMID 33094617.
  3. Van Rooyen, D.; Gent, R.; Barnard, L.; Swart, A. C. (2018). "The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway". The Journal of Steroid Biochemistry and Molecular Biology. 178: 203–212. doi:10.1016/j.jsbmb.2017.12.014. PMID 29277707. S2CID 3700135.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.