CYP2W1

CYP2W1 (cytochrome P450, family 2, subfamily W, polypeptide 1) is a protein that in humans is encoded by the CYP2W1 gene.[5]

CYP2W1
Identifiers
AliasesCYP2W1, cytochrome P450 family 2 subfamily W member 1
External IDsOMIM: 615967 MGI: 3616076 HomoloGene: 69239 GeneCards: CYP2W1
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7p22.3Start983,181 bp[1]
End989,640 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

54905

545817

Ensembl

ENSG00000073067

ENSMUSG00000029541

UniProt

Q8TAV3

E9Q816

RefSeq (mRNA)

NM_017781

NM_001160265

RefSeq (protein)

NP_060251

NP_001153737

Location (UCSC)Chr 7: 0.98 – 0.99 MbChr 5: 139.35 – 139.36 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.[6] CYP2W1 is an interesting enzyme since it is mainly expressed in tumors and not in normal human tissue.

References

  1. GRCh38: Ensembl release 89: ENSG00000073067 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029541 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gerhard DS, Wagner L, Feingold EA, et al. (October 2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  6. "Entrez Gene: CYP2W1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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