Influenza A virus subtype H1N2

Influenza A virus subtype H1N2 (A/H1N2) is a subtype of the species Influenza A virus (sometimes called bird flu virus). It is currently endemic in both human and pig populations.

Influenza A virus subtype H1N2
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Insthoviricetes
Order: Articulavirales
Family: Orthomyxoviridae
Genus: Alphainfluenzavirus
Species: Influenza A virus
Serotype: Influenza A virus subtype H1N2

H1N1, H1N2, and H3N2 are the only known Influenza A virus subtypes currently circulating among humans.

The virus does not cause more severe illness than other influenza viruses, and no unusual increases in influenza activity have been associated with it.

History

Between December 1988 and March 1989, 19 influenza H1N2 virus isolates were identified in 6 cities in China, but the virus did not spread further.[1]

A(H1N2) was identified during the 2001–02 flu season (northern hemisphere) in Canada, the U.S., Ireland, Latvia, France, Romania, Oman, India, Malaysia, and Singapore with earliest documented outbreak of the virus occurring in India on May 31, 2001.

On February 6, 2002, the World Health Organization (WHO) in Geneva and the Public Health Laboratory Service (PHLS) in the United Kingdom reported the identification influenza A(H1N2) virus from humans in the UK, Israel, and Egypt.

The 2001–02 Influenza A(H1N2) Wisconsin strain appears to have resulted from the reassortment of the genes of the currently circulating influenza A(H1N1) and A(H3N2) subtypes.

Because the hemagglutinin protein of the virus is similar to that of the currently circulating A(H1N1) viruses and the neuraminidase protein is similar to that of the current A(H3N2) viruses, the seasonal flu vaccine should provide good protection against influenza virus as well as protection against the currently circulating seasonal A(H1N1), A(H3N2), and B viruses.

In October 2020, a new case was confirmed in Alberta, Canada and was the first confirmed case in a human in the country.[2]

References

  •  This article incorporates public domain material from the Centers for Disease Control and Prevention document: "Questions and Answers About Influenza A(H1N2) Viruses".
  •  This article incorporates public domain material from the Centers for Disease Control and Prevention document: "2001-02 INFLUENZA SEASON SUMMARY".
  1. Guo, YJ; Xu, XY; Cox, NJ (1992). "Human influenza A (H1N2) viruses isolated from China". The Journal of General Virology. 73 (2): 383–7. doi:10.1099/0022-1317-73-2-383. PMID 1538194.
  2. "Alberta confirms first Canadian case of H1N2 flu virus in a human". CalgaryHerald. 2020-11-04. Retrieved 4 November 2020.
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