DUSP19

Dual specificity protein phosphatase 19 is an enzyme that in humans is encoded by the DUSP19 gene.[4]

DUSP19
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDUSP19, DUSP17, LMWDSP3, SKRP1, TS-DSP1, dual specificity phosphatase 19
External IDsOMIM: 611437 MGI: 1915332 HomoloGene: 41565 GeneCards: DUSP19
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q32.1Start183,078,559 bp[1]
End183,100,008 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

142679

68082

Ensembl

ENSG00000162999

ENSMUSG00000027001

UniProt

Q8WTR2

Q8K4T5
Q99N12

RefSeq (mRNA)

NM_001142314
NM_080876
NM_001321519

NM_024438

RefSeq (protein)

NP_001135786
NP_001308448
NP_543152

NP_077758

Location (UCSC)Chr 2: 183.08 – 183.1 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

DUSP19 has been shown to interact with ASK1[5] and MAP2K7.[5][6]

References

  1. GRCh38: Ensembl release 89: ENSG00000162999 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Entrez Gene: DUSP19 dual specificity phosphatase 19".
  5. Zama T, Aoki R, Kamimoto T, Inoue K, Ikeda Y, Hagiwara M (June 2002). "Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway". The Journal of Biological Chemistry. 277 (26): 23919–26. doi:10.1074/jbc.M200838200. PMID 11959862.
  6. Zama T, Aoki R, Kamimoto T, Inoue K, Ikeda Y, Hagiwara M (June 2002). "A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway". The Journal of Biological Chemistry. 277 (26): 23909–18. doi:10.1074/jbc.M200837200. PMID 11959861.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q8WTR2 (Human Dual specificity protein phosphatase 19 (DUSP19)) at the PDBe-KB.


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