Interstate 64

The Spoede Road overpass in Missouri above I-64, demolished in June 2008

In Missouri, the stretch was originally labeled as the Daniel Boone Expressway then only as US-40, and as such, is still known to some locals in the St. Louis area as Highway 40, even though the road has been designated as both I-64 and US-40 since 1988. This road is also the southernmost portion of the Avenue of the Saints. An interchange at Highway N O'Fallon, Missouri opened on December 13, 2004. This interchange also accommodates the tie-in of the Missouri Route 364 freeway to I-64. In April 2007, construction started to rebuild 10.5 miles (16.9 km) of I-64 in St. Louis, Missouri, from Spoede Road to Kingshighway. This project included repaving the entire road, rebuilding the overpasses and interchanges, adding a fourth lane between Spoede Road and I-170, and connecting I-64 to I-170 in all directions. Construction resulted in the complete closure of portions of the expressway in 2008 and 2009. In 2008, I-64 was closed from I-270 to I-170, re-opening December 15, 2008. Beginning December 15, 2008, I-64 from I-170 to Kingshighway was closed. On December 6, 2009,[3] with a grand opening ceremony and dedication, Interstate 64 was completed in its entire length in Missouri from the Poplar Street Bridge to I-70 in Wentzville.[4] As of December 7, 2009, I-64 is now complete and signed all the way to Interstate 70 in Wentzville.[5] All stoplights have been removed. The portion of Interstate 64 in St. Louis has been named the Jack Buck Memorial Highway, in honor of the late sportscaster.

I-64 crosses the Poplar Street Bridge from Missouri to Illinois

I-64 enters Illinois from St. Louis, Missouri, via the Poplar Street Bridge, where it overlaps I-55 as it crosses the Mississippi River. After crossing the city of East St. Louis and the rest of suburban St. Clair County, the freeway heads southeast through rural Southern Illinois. Shortly after passing Mid-America Airport at Exit 23, I-64 enters Clinton County, then Washington County. After providing access to towns such as Carlyle, Breese, Nashville, and Centralia, the freeway overlaps I-57 through the Mt. Vernon area for approximately five miles. East of Mt. Vernon in Illinois, services along I-64 are slim to none. It is an almost completely flat and empty freeway, crossing Jefferson, Wayne, and White counties as it progresses east toward Indiana and the Evansville area. East of the St. Louis area, there are numerous oil wells dotting the landscape.

The section from IL 127 to I-57 opened on October 4, 1974.[6] The section from IL 161 to IL 127 opened in December 1973.[7] The section in the Metro East, except for a short section near I-55/70, opened on December 23, 1975.[8] The section from US 460 (later IL 142) to US 45 opened on August 7, 1975.[9]

I-64 crosses the Sherman Minton Bridge in New Albany, Indiana

I-64 crosses the Wabash River and enters the state of Indiana. It passes Griffin (exit 4/State Road 69) and Poseyville (exit 12/State Road 165), and also passes under nearby State Road 68 (no direct interchange serves State Road 68, though one can access said route from either State Road 165 or 65) then passes three officially marked exits for Evansville (State Road 65, US 41, and Interstate 69 [formerly Interstate 164]) then proceeds through part of the scenic Hoosier National Forest, with exits leading to Dale and Huntingburg (Exits 57A-B/US 231), Santa Claus and Ferdinand (exit 63/State Road 162), French Lick and Tell City (exit 79/State Road 37), and Indiana's first state capital, Corydon (exit 105/State Road 135).

Near milepost 61, there is a time change from Central Time Zone (Spencer County) to Eastern Time Zone (Dubois County). Between mileposts 60 and 80, I-64 crosses the Central/Eastern time zone boundary 5 times. As with all time zone changes on highways maintained by the Indiana Department of Transportation, these changes in time zone are not marked with any roadside signage.

Between Evansville and New Albany, I-64 intersects a few major north-south arterial highways, such as U.S. 231, Indiana 37, Indiana 135 and offers access to Interstate 65 to Indianapolis via Interstate 265 before crossing into Kentucky on the Sherman Minton Bridge.

The 123-mile route in Indiana can be described as being somewhat winding, especially the farther east one travels within the state. The longest straight line distance along the route is the 9-mile stretch from the Indiana 65 exit to the 26 mile marker, 1 mile east of U.S. 41. There are many points along the route where the two halves of the highway are nearly 500 feet apart, especially around the Hoosier National Forest and points to the east. In addition, there are several points, especially in the very sharp valleys along its route in Dubois, Perry, Crawford and Harrison Counties, where the highway towers more than 100 feet above the surrounding terrain.

Streaking lights on I-64 as seen from the horse/bike bridge at Seneca Park in Louisville, Kentucky.

Interstate 64 enters Kentucky at Louisville, paralleling the Ohio River along the Riverfront Expressway. It intersects with several downtown interchanges before coming to the Kennedy Interchange, where it intersects Interstate 65 and Interstate 71 in a tangle of ramps often referred to as the "Spaghetti Junction". Moving eastward, I-64 passes through Shelbyville, Frankfort, Midway, Lexington, Winchester, Mount Sterling, Owingsville, and Morehead, before leaving the state near Ashland at Catlettsburg. It overlaps Interstate 75 as it makes an arc around the northeast of Lexington's urban core, with the exit numbers for I-75 used for the concurrent portion. The two interstates separate a few miles east of downtown Lexington.

Toll booths on the West Virginia Turnpike

Interstate 64 travels for 184 miles (296 km) within the state of West Virginia, passing by the major cities of Huntington, Beckley, and Lewisburg, and directly through the Capital city of Charleston. It has only two major junctions within the state: Interstate 77 in Charleston and in Beckley. It also crosses the Kanawha River a total of four times in a 20-mile (32 km) stretch (twice west of Charleston, immediately before entering the downtown Charleston area, then approximately 5 miles (8.0 km) east of downtown Charleston in Kanawha City).

Between I-64's two junctions with I-77, I-64 and I-77 overlap. From the final crossing of the Kanawha River east of Charleston to their split at Exit 40 south of Beckley, the two Interstates are tolled, forming a part of the West Virginia Turnpike.

While the two expressways overlap, the exit signs are those for Interstate 77. Thus, eastbound travelers entering from Kentucky will see exit numbers increase until Exit 60, at which time Interstate 77's exit numbers are used, decreasing from Exit 100.

Southern terminus of the I-81/I-64 overlap near Lexington, Virginia

Interstate 64 in Virginia runs east–west through central Virginia from West Virginia via Covington, Lexington, Staunton, and Charlottesville to Richmond. From Lexington to Staunton, it overlaps Interstate 81 (using I-81 exit numbers). In Richmond, it overlaps Interstate 95.[10] From Richmond, Interstate 64 continues southeasterly through Newport News and Hampton to the Hampton Roads Bridge-Tunnel, and then through Norfolk and a small portion of Virginia Beach to end in Chesapeake.[11]

I-64 itself does not reach the Oceanfront area of Virginia Beach, as it continues through the western portion of Virginia Beach as part of the circumferential Hampton Roads Beltway. At its terminus, East I-64 runs over 12 miles westbound (and West I-64 eastbound), as the route forms a fishhook around Norfolk. Interstate 264 intersects the beltway, providing access to other parts of Norfolk and Chesapeake, and extending east to the Oceanfront.

Access to the Oceanfront area is accomplished from I-64 via a portion of Interstate 264, a roadway originally built as the Virginia Beach Expressway, funded by tolls to retire revenue bonds.