Suprofen
Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica[1] that was marketed as 1% eye drops under the trade name Profenal.
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| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Routes of administration | Oral, eye drops |
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| Protein binding | 20% |
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| ECHA InfoCard | 100.050.071  |
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| Formula | C14H12O3S |
| Molar mass | 260.31 g·mol−1 |
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Uses
Suprofen was originally used as tablet, but oral uses have been discontinued due to renal effects.[2] It was subsequently used exclusively as a topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.[3] This application has been discontinued as well, at least in the US.[4]
References
- DE 2353357, Janssen PA, Van Daele GH, Boey JM, "Antiphlogistic aroyl-substituted phenylacetic acid derivatives", issued 1974
- Nies AS (1988). "Renal effects of nonsteroidal anti-inflammatory drugs". Agents and Actions. Supplements. 24: 95–106. doi:10.1007/978-3-0348-9160-8_9. ISBN 978-3-0348-9931-4. PMID 3142236.
- "Pharmacy Compounding". Guidance for FDA Staff and Industry Compliance Policy Guides Manual. U.S. Food and Drug Administration. Archived from the original on 1 January 2009.
- "Suprofen ophthalmic". Drugs.com.
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