DMPX
DMPX (3,7-dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity to A2 adenosine receptors, in contrast to the A1 subtype receptors.[1] DMPX had 28× and 15× higher potency than caffeine in blocking peripheral and central NECA-responses. The locomotor stimulation caused by DMPX (ED50 10 μmol/kg) was similarly higher than caffeine.[1]
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| ECHA InfoCard | 100.162.258  |
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| Formula | C10H10N4O2 |
| Molar mass | 218.216 g·mol−1 |
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See also
- DPCPX
- 8-PT
- CPX (8-CPT)
- 8-Chlorotheophylline
- Theophylline
References
- Seale TW, Abla KA, Shamim MT, Carney JM, Daly JW (1988). "3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs". Life Sciences. 43 (21): 1671–84. doi:10.1016/0024-3205(88)90478-x. PMID 3193854.
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See also: Receptor/signaling modulators | |||||||||||
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