2-Propanoyl-3-(4-isopropylphenyl)-tropane
2-Propanoyl-3-(4-isopropylphenyl)-tropane (WF-31, PIT) is a cocaine analogue which acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). Research shows WF-31 to be approximately ten times more potent than cocaine at binding to the serotonin transporter and at inhibiting its reuptake.[1]
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| Identifiers | |
|---|---|
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| Chemical and physical data | |
| Formula | C20H29NO |
| Molar mass | 299.458 g·mol−1 |
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See also
References
- Porrino LJ, Miller M, Hedgecock AA, Thornley C, Matasi JJ, Davies HM (September 1997). "Local cerebral metabolic effects of the novel cocaine analog, WF-31: comparisons to fluoxetine". Synapse (New York, N.Y.). 27 (1): 26–35. doi:10.1002/(SICI)1098-2396(199709)27:1<26::AID-SYN3>3.0.CO;2-F. PMID 9268062.
| 2-Carboxymethyl Esters | |
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| (3,4-Disubstituted Phenyl)-tropanes | |
| Arylcarboxy | |
| Carboxyalkyl | |
| Acyl | |
| β,α Stereochemistry | |
| α,β Stereochemistry | |
| Heterocycles: 3-Substituted-isoxazol-5-yl | |
| Heterocycles: 3-Substituted-1,2,4-oxadiazole | |
| N-alkyl | |
| N-replaced (S,O,C) | |
| Irreversible |
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| Nortropanes (N-demethylated) | |
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